Literature DB >> 3883303

'Like a shrivelled blood orange'--bilirubin, jaundice, and phototherapy.

A F McDonagh, D A Lightner.   

Abstract

The biochemistry of bilirubin is reviewed with particular reference to newborn infants. The formation, properties, and metabolism of bilirubin are summarized and the importance of molecular shape, hydrogen-bonding, and polarity on the biologic disposition of bilirubin is emphasized. The chemical basis for the subtle influence of visible (blue) light on bilirubin structure and metabolism is explained, and recent concepts of the mechanism of phototherapy are presented. A glossary of current jargon is appended.

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Year:  1985        PMID： 3883303

Source DB:  PubMed          Journal:  Pediatrics        ISSN： 0031-4005            Impact factor:   7.124


  17 in total

1.  Solartheology, heliotherapy, phototherapy, and biologic effects: a historical overview.

Authors:  H Bloch
Journal:  J Natl Med Assoc       Date:  1990-07       Impact factor: 1.798

Review 2.  Treatment of acne vulgaris during pregnancy and lactation.

Authors:  Y L Kong; H L Tey
Journal:  Drugs       Date:  2013-06       Impact factor: 9.546

3.  Interscapular site for transcutaneous bilirubin measurement in preterm infants: a better and safer screening site.

Authors:  A Yaser; L Tooke; N Rhoda
Journal:  J Perinatol       Date:  2014-01-09       Impact factor: 2.521

4.  Sister Jean Ward, phototherapy, and jaundice: a unique human and photochemical interaction.

Authors:  M J Maisels
Journal:  J Perinatol       Date:  2015-06-11       Impact factor: 2.521

5.  Early formation of bilirubin isomers during phototherapy for neonatal jaundice: effects of single vs. double fluorescent lamps vs. photodiodes.

Authors:  Khalaf Mreihil; Poul Madsen; Britt Nakstad; Jūratė Šaltytė Benth; Finn Ebbesen; Thor Willy Ruud Hansen
Journal:  Pediatr Res       Date:  2015-03-20       Impact factor: 3.756

Review 6.  Principles of drug biodisposition in the neonate. A critical evaluation of the pharmacokinetic-pharmacodynamic interface (Part II).

Authors:  J B Besunder; M D Reed; J L Blumer
Journal:  Clin Pharmacokinet       Date:  1988-05       Impact factor: 6.447

7.  Renal handling of bilirubin photoderivatives.

Authors:  M M Elías; E J Comin; J E Ochoa; E A Rodríguez Garay
Journal:  Experientia       Date:  1987-08-15

Review 8.  Use of phototherapy for neonatal hyperbilirubinemia. Fetus and Newborn Committee, Canadian Paediatric Society.

Authors: 
Journal:  CMAJ       Date:  1986-06-01       Impact factor: 8.262

9.  The effect of bilirubin photoisomers on unbound-bilirubin concentrations estimated by the peroxidase method.

Authors:  S Itoh; T Yamakawa; S Onishi; K Isobe; M Manabe; K Sasaki
Journal:  Biochem J       Date:  1986-10-15       Impact factor: 3.857

10.  Wavelength-dependence of the relative rate constants for the main geometric and structural photoisomerization of bilirubin IX alpha bound to human serum albumin. Demonstration of green light at 510 nm as the most effective wavelength in photochemical changes from (ZZ)-bilirubin IX alpha to (EZ)-cyclobilirubin IX alpha via (EZ)-bilirubin.

Authors:  S Onishi; S Itoh; K Isobe
Journal:  Biochem J       Date:  1986-05-15       Impact factor: 3.857
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