Literature DB >> 3882692

Primary structure of human lymphotoxin derived from 1788 lymphoblastoid cell line.

B B Aggarwal, W J Henzel, B Moffat, W J Kohr, R N Harkins.   

Abstract

The amino acid sequence of human lymphotoxin derived from a 1788 lymphoblastoid cell line was determined. Peptide fragments obtained by trypsin, lysine-C peptidase, cyanogen bromide, and acetic acid cleavage of the intact protein were purified by reverse-phase high performance liquid chromatography and analyzed by amino acid composition and by automated Edman degradation. The protein is 171 amino acids long with a molecular weight of 18,664. It contains one asparagine-linked glycosylation site and lacks cysteine. The salient features of the amino acid sequence of lymphotoxin are described.

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Year:  1985        PMID： 3882692

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  33 in total

1.  Haplotypic polymorphisms of the TNFB gene.

Authors:  L J Abraham; D C Du; K Zahedi; R L Dawkins; A S Whitehead
Journal:  Immunogenetics       Date:  1991       Impact factor: 2.846

2.  Relationship between a novel human cytotoxin (factor 2) produced by a B cell line (Karpas 160) and phorbol-myristate-acetate-associated cytotoxicity.

Authors:  J Ni; A Karpas
Journal:  Clin Exp Immunol       Date:  1992-05       Impact factor: 4.330

3.  Coexpression network based on natural variation in human gene expression reveals gene interactions and functions.

Authors:  Renuka R Nayak; Michael Kearns; Richard S Spielman; Vivian G Cheung
Journal:  Genome Res       Date:  2009-10-01       Impact factor: 9.043

4.  The amino acid sequence of component 7c, a type II intermediate-filament protein from wool.

Authors:  L G Sparrow; C P Robinson; D T McMahon; M R Rubira
Journal:  Biochem J       Date:  1989-08-01       Impact factor: 3.857

5.  Neutrophil activation on biological surfaces. Massive secretion of hydrogen peroxide in response to products of macrophages and lymphocytes.

Authors:  C F Nathan
Journal:  J Clin Invest       Date:  1987-12       Impact factor: 14.808

6.  Identity of human B-cell line cytotoxic lymphokine with tumor necrosis factor type beta.

Authors:  H I Yamanaka; A Karpas
Journal:  Proc Natl Acad Sci U S A       Date:  1989-02       Impact factor: 11.205

Review 7.  Historical perspectives on tumor necrosis factor and its superfamily: 25 years later, a golden journey.

Authors:  Bharat B Aggarwal; Subash C Gupta; Ji Hye Kim
Journal:  Blood       Date:  2011-11-03       Impact factor: 22.113

Review 8.  An overview of the history and biologic properties of tumor necrosis factors.

Authors:  M R Shalaby; D Pennica; M A Palladino
Journal:  Springer Semin Immunopathol       Date:  1986

9.  Purified native and recombinant human alpha lymphotoxin [tumor necrosis factor (TNF)-beta] induces inflammatory reactions in normal skin.

Authors:  B J Averbook; R S Yamamoto; T R Ulich; E W Jeffes; I Masunaka; G A Granger
Journal:  J Clin Immunol       Date:  1987-07       Impact factor: 8.317

10.  Isolation and specificity of a Mr 74,000 cholesteryl ester transfer protein from human plasma.

Authors:  A S Jarnagin; W Kohr; C Fielding
Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205
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