Literature DB >> 388230

Identification and processing of proglucagon in pancreatic islets.

C Patzelt, H S Tager, R J Carroll, D F Steiner.   

Abstract

Immunoprecipitation and tryptic peptide analysis of newly synthesized proteins from rat islets have identified an 18,000 molecular weight (MW) protein as proglucagon. Conversion of this precursor was kinetically similar to the conversion of proinsulin and resulted in the formation of both pancreatic glucagon and a 10,000-MW protein lacking this hormonal sequence.

Entities:  

Mesh：

Substances：

Year:  1979        PMID： 388230     DOI： 10.1038/282260a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  30 in total

1.  Production of recombinant human glucagon in the form of a fusion protein in Escherichia coli; recovery of glucagon by sequence-specific digestion.

Authors:  J Ishizaki; M Tamaki; M Shin; H Tsuzuki; K Yoshikawa; H Teraoka; N Yoshida
Journal:  Appl Microbiol Biotechnol       Date:  1992-01       Impact factor: 4.813

Review 2.  Glucagon-like peptide 1 (GLP-1).

Authors:  T D Müller; B Finan; S R Bloom; D D'Alessio; D J Drucker; P R Flatt; A Fritsche; F Gribble; H J Grill; J F Habener; J J Holst; W Langhans; J J Meier; M A Nauck; D Perez-Tilve; A Pocai; F Reimann; D A Sandoval; T W Schwartz; R J Seeley; K Stemmer; M Tang-Christensen; S C Woods; R D DiMarchi; M H Tschöp
Journal:  Mol Metab       Date:  2019-09-30       Impact factor: 7.422

3.  Molecular cloning and amino acid sequence of the precursor form of bovine adrenodoxin: evidence for a previously unidentified COOH-terminal peptide.

Authors:  T Okamura; M E John; M X Zuber; E R Simpson; M R Waterman
Journal:  Proc Natl Acad Sci U S A       Date:  1985-09       Impact factor: 11.205

4.  Immunohistochemical localization of glucagon-like peptide 1. Use of poly- and monoclonal antibodies.

Authors:  T Kauth; J Metz
Journal:  Histochemistry       Date:  1987

Review 5.  Multiple forms of gastroenteropancreatic hormones.

Authors:  G B Irvine; R F Murphy
Journal:  Gut       Date:  1981-12       Impact factor: 23.059

6.  Pancreatic preproglucagon cDNA contains two glucagon-related coding sequences arranged in tandem.

Authors:  P K Lund; R H Goodman; P C Dee; J F Habener
Journal:  Proc Natl Acad Sci U S A       Date:  1982-01       Impact factor: 11.205

7.  Tumour calcitonin. Interaction with specific calcitonin receptors.

Authors:  J Ham; M L Ellison; J Lumsden
Journal:  Biochem J       Date:  1980-09-15       Impact factor: 3.857

Review 8.  Pancreatic glucagonoma with and without syndrome. Immunocytochemical study of 5 tumour cases and review of the literature.

Authors:  E Ruttman; G Klöppel; G Bommer; M Kiehn; P U Heitz
Journal:  Virchows Arch A Pathol Anat Histol       Date:  1980

9.  Simultaneous immunohistochemical localization of gastrin releasing peptide (GRP) and calcitonin (CT) in human bronchial endocrine-type cells.

Authors:  Y Tsutsumi; R Y Osamura; K Watanabe; N Yanaihara
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1983

10.  Differential inhibitory action of cationic amino acids on protein synthesis in pancreatic rat islets.

Authors:  C Patzelt
Journal:  Diabetologia       Date:  1988-04       Impact factor: 10.122
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.