Literature DB >> 3880988

Prostacyclin and thromboxane A2 production by human cardiac atrial tissues.

J Mehta, P Mehta.   

Abstract

We examined the generation of prostacyclin and thromboxane A2 in the right atrial tissues obtained from patients undergoing coronary bypass surgery. In all instances, the capability of atrial tissues to produce these potent prostaglandins was identified. The identity of prostacyclin and thromboxane A2 was confirmed by use of specific radioimmunoassays of stable metabolites and by use of specific thromboxane A2 synthetase and cyclo-oxygenase inhibitors.

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Year:  1985        PMID: 3880988     DOI: 10.1016/0002-8703(85)90407-7

Source DB:  PubMed          Journal:  Am Heart J        ISSN: 0002-8703            Impact factor:   4.749


  3 in total

1.  Effects of tetramethylpyrazine on the release of PGI2 and TXA2 in the hypoxic isolated rat heart.

Authors:  J Feng; R Liu; G Wu; S Tang
Journal:  Mol Cell Biochem       Date:  1997-02       Impact factor: 3.396

2.  Thromboxane receptor density is increased in human cardiovascular disease with evidence for inhibition at therapeutic concentrations by the AT(1) receptor antagonist losartan.

Authors:  S D Katugampola; A P Davenport
Journal:  Br J Pharmacol       Date:  2001-12       Impact factor: 8.739

3.  Possible role of thromboxane A2 in remote hind limb preconditioning-induced cardioprotection.

Authors:  Roohani Sharma; Puneet Kaur Randhawa; Nirmal Singh; Amteshwar Singh Jaggi
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2015-11-03       Impact factor: 3.000

  3 in total

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