Literature DB >> 3880769

Immunologic identification of both plasma and human renal inactive renin as prorenin.

J Bouhnik, J A Fehrentz, F X Galen, R Seyer, G Evin, B Castro, J Menard, P Corvol.   

Abstract

Antibodies were raised against a synthetic tetradecapeptide which is a component of the non-renin portion (prosegment) of human renin precursor. Inactive renin from human kidney and plasma strongly adsorbed to a gel coupled to immunoglobulins purified from such an antiserum. These results suggest that renal and circulating inactive human renins contain in their structure the prosegment of prorenin.

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Year:  1985        PMID： 3880769     DOI： 10.1210/jcem-60-2-399

Source DB:  PubMed          Journal:  J Clin Endocrinol Metab        ISSN： 0021-972X            Impact factor:   5.958


  11 in total

Review 1.  Ovarian hyperstimulation syndrome: a review of pathophysiology.

Authors:  P A Bergh; D Navot
Journal:  J Assist Reprod Genet       Date:  1992-10       Impact factor: 3.412

2.  Similarity between physicochemical properties of recombinant rat prorenin and native inactive renin.

Authors:  M Hosoi; S Kim; T Yamauchi; T Watanabe; K Murakami; F Suzuki; A Takahashi; Y Nakamura; K Yamamoto
Journal:  Biochem J       Date:  1991-05-01       Impact factor: 3.857

Review 3.  Circulating and tissue angiotensin systems.

Authors:  D J Campbell
Journal:  J Clin Invest       Date:  1987-01       Impact factor: 14.808

4.  Cyclical secretion of prorenin during the menstrual cycle: synchronization with luteinizing hormone and progesterone.

Authors:  J E Sealey; S A Atlas; N Glorioso; H Manapat; J H Laragh
Journal:  Proc Natl Acad Sci U S A       Date:  1985-12       Impact factor: 11.205

5.  Isolation of renin-producing human cells by transfection with three simian virus 40 mutants.

Authors:  F Pinet; M T Corvol; F Dench; J Bourguignon; J Feunteun; J Menard; P Corvol
Journal:  Proc Natl Acad Sci U S A       Date:  1985-12       Impact factor: 11.205

6.  Renin activation in juvenile secretory granules? Immunocytochemical experiments with an antiserum directed against the prosegment of human renin.

Authors:  R Taugner; K Murakami; S J Kim
Journal:  Histochemistry       Date:  1986

7.  Characterization of human prorenin expressed in mammalian cells from cloned cDNA.

Authors:  L C Fritz; A E Arfsten; V J Dzau; S A Atlas; J D Baxter; J C Fiddes; J Shine; C L Cofer; P Kushner; P A Ponte
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205

8.  Secretion control for active and inactive renin: effect of ouabain on release from rabbit kidney cortex slices.

Authors:  L M Ginesi; A R Noble
Journal:  J Physiol       Date:  1986-10       Impact factor: 5.182

9.  Coexistence of renin and cathepsin B in epithelioid cell secretory granules.

Authors:  R Taugner; C P Bührle; R Nobiling; H Kirschke
Journal:  Histochemistry       Date:  1985

10.  Response of plasma prorenin and active renin to chronic and acute alterations of renin secretion in normal humans. Studies using a direct immunoradiometric assay.

Authors:  E B Toffelmire; K Slater; P Corvol; J Menard; M Schambelan
Journal:  J Clin Invest       Date:  1989-02       Impact factor: 14.808
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