Literature DB >> 3879759

Preferential paternal transmission of the diabetogenic supratype marked by HLA B18 BfF1 DR3.

P H Kay, A N Wilton, R L Dawkins.   

Abstract

Examination of transmission of the diabetogenic supratype B18 BfF1 DR3 revealed that this supratype is inherited more frequently than expected from fathers. These data suggest an explanation for increased susceptibility to development and earlier onset of insulin dependent diabetes mellitus in offspring of diabetic fathers.

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Year:  1985        PMID: 3879759     DOI: 10.1111/j.1744-313x.1985.tb01065.x

Source DB:  PubMed          Journal:  J Immunogenet        ISSN: 0305-1811


  2 in total

1.  Familial insulin-dependent diabetes mellitus (IDDM) epidemiology: standardization of data for the DIAMOND Project. The WHO Multinational Project for Childhood Diabetes Group.

Authors: 
Journal:  Bull World Health Organ       Date:  1991       Impact factor: 9.408

2.  Inheritance of MHC class II genes in IDDM studied in population-based affected and control families.

Authors:  I Kockum; R Wassmuth; E Holmberg; B Michelsen; A Lernmark
Journal:  Diabetologia       Date:  1994-11       Impact factor: 10.122

  2 in total

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