Literature DB >> 3879199

A simple colorimetric method for the determination of primaquine metabolites in urine.

J K Baker, J D McChesney, L Jorge.   

Abstract

A simple method of screening large numbers of urine samples for the presence of primaquine metabolites has been developed using a commercially available diazonium salt reagent and an extraction cartridge. The extraction requires only 1.0 ml of urine and is selective for acidic or neutral primaquine metabolites. With primaquine-dosed rats, primaquine metabolites could be detected 36 hours after administration of the drug. The sensitivity of the method was found to be approximately 400 mug/l.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 3879199      PMCID： PMC2536454     

Source DB:  PubMed          Journal:  Bull World Health Organ        ISSN： 0042-9686            Impact factor:   9.408


  2 in total

1.  Spectrophotometric assay of primaquine in plasma.

Authors:  R N Prasad; S K Garg; R C Mahajan; N K Ganguly
Journal:  Indian J Med Res       Date:  1983-03       Impact factor: 2.375

2.  High-performance liquid chromatographic analysis of the metabolism of primaquine and the identification of a new mammalian metabolite.

Authors:  J K Baker; J D McChesney; C D Hufford; A M Clark
Journal:  J Chromatogr       Date:  1982-06-11
  2 in total
  1 in total

1.  Characterization of the urinary metabolites of primaquine in rats.

Authors:  J K Baker; J D McChesney; L F Jorge
Journal:  Pharm Res       Date:  1986-06       Impact factor: 4.200
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.