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Literature DB >> 3879172

Size of the inositol 1,4,5-trisphosphate-sensitive calcium pool in guinea-pig hepatocytes.

Abstract

Permeabilized hepatocytes accumulated 45Ca2+ into a non-mitochondrial pool when provided with ATP. 45Ca2+ efflux from this pool was revealed by removal of ATP with glucose and hexokinase or by inhibiting uptake with NaVO3. The effect of inositol 1,4,5-trisphosphate (IP3) on 45Ca2+ efflux from the pool was investigated. IP3 (5 microM) evoked a rapid increase in the rate of 45Ca2+ efflux. Kinetic analysis of the effect of IP3 indicated the existence of two distinct Ca2+ fractions within the pool; only one, accounting for about one-third of the ATP-dependent Ca2+ content of the pool, was responsive to IP3. The effect of IP3 on 45Ca2+ efflux from the non-mitochondrial pool does not require ATP, a finding that is inconsistent with a previous suggestion that this effect may be mediated by protein phosphorylation.

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Year: 1985 PMID： 3879172 PMCID： PMC1152898 DOI： 10.1042/bj2320435

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

20 in total

1. Concerted regulation of cardiac sarcoplasmic reticulum calcium transport by cyclic adenosine monophosphate dependent and calcium--calmodulin-dependent phosphorylations.

Authors: C J Le Peuch; J Haiech; J G Demaille
Journal: Biochemistry Date: 1979-11-13 Impact factor: 3.162

2. Actions of inositol phosphates on Ca2+ pools in guinea-pig hepatocytes.

Authors: G M Burgess; R F Irvine; M J Berridge; J S McKinney; J W Putney
Journal: Biochem J Date: 1984-12-15 Impact factor: 3.857

3. Net calcium fluxes in rat parotid acinar cells: evidence for a hormone-sensitive calcium pool in or near the plasma membrane.

Authors: J Poggioli; J W Putney
Journal: Pflugers Arch Date: 1982-01 Impact factor: 3.657

4. Alpha-adrenergic stimulation of potassium efflux in guinea-pig hepatocytes may involve calcium influx and calcium release.

Authors: L M DeWitt; J W Putney
Journal: J Physiol Date: 1984-01 Impact factor: 5.182

5. Exchange characteristics of the noradrenaline-sensitive calcium store in vascular smooth muscle cells or rabbit ear artery.

Authors: R Casteels; G Droogmans
Journal: J Physiol Date: 1981-08 Impact factor: 5.182

6. The second messenger linking receptor activation to internal Ca release in liver.

Authors: G M Burgess; P P Godfrey; J S McKinney; M J Berridge; R F Irvine; J W Putney
Journal: Nature Date: 1984 May 3-9 Impact factor: 49.962

7. myo-Inositol 1,4,5-trisphosphate. A second messenger for the hormonal mobilization of intracellular Ca2+ in liver.

Authors: S K Joseph; A P Thomas; R J Williams; R F Irvine; J R Williamson
Journal: J Biol Chem Date: 1984-03-10 Impact factor: 5.157

8. Calcium pools in saponin-permeabilized guinea pig hepatocytes.

Authors: G M Burgess; J S McKinney; A Fabiato; B A Leslie; J W Putney
Journal: J Biol Chem Date: 1983-12-25 Impact factor: 5.157

9. Nature of the receptor-regulated calcium pool in the rat parotid gland.

Authors: D L Aub; J S McKinney; J W Putney
Journal: J Physiol Date: 1982-10 Impact factor: 5.182

10. Effects of quinine and apamin on the calcium-dependent potassium permeability of mammalian hepatocytes and red cells.

Authors: G M Burgess; M Claret; D H Jenkinson
Journal: J Physiol Date: 1981-08 Impact factor: 5.182

15 in total

1. Effects of vasopressin and La3+ on plasma-membrane Ca2+ inflow and Ca2+ disposition in isolated hepatocytes. Evidence that vasopressin inhibits Ca2+ disposition.

Authors: B P Hughes; S E Milton; G J Barritt
Journal: Biochem J Date: 1986-09-15 Impact factor: 3.857

Review 2. Inositol trisphosphate receptor Ca2+ release channels.

Authors: J Kevin Foskett; Carl White; King-Ho Cheung; Don-On Daniel Mak
Journal: Physiol Rev Date: 2007-04 Impact factor: 37.312

3. Molecular target sizes of inositol 1,4,5-trisphosphate receptors in liver and cerebellum.

Authors: D L Nunn; B V Potter; C W Taylor
Journal: Biochem J Date: 1990-01-15 Impact factor: 3.857

4. The size of inositol 1,4,5-trisphosphate-sensitive Ca2+ stores depends on inositol 1,4,5-trisphosphate concentration.

Authors: C W Taylor; B V Potter
Journal: Biochem J Date: 1990-02-15 Impact factor: 3.857

5. Inositol 1,4,5-trisphosphorothioate, a stable analogue of inositol trisphosphate which mobilizes intracellular calcium.

Authors: C W Taylor; M J Berridge; A M Cooke; B V Potter
Journal: Biochem J Date: 1989-05-01 Impact factor: 3.857

6. Effects of Ca2+ on phosphoinositide breakdown in exocrine pancreas.

Authors: C W Taylor; J E Merritt; J W Putney; R P Rubin
Journal: Biochem J Date: 1986-09-15 Impact factor: 3.857

7. Synthesis and application of photoaffinity analogues of inositol 1,4,5-trisphosphate selectively substituted at the 1-phosphate group.

Authors: R Schäfer; M Nehls-Sahabandu; B Grabowsky; M Dehlinger-Kremer; I Schulz; G W Mayr
Journal: Biochem J Date: 1990-12-15 Impact factor: 3.857

8. Subcellular distribution of the calcium-storing inositol 1,4,5-trisphosphate-sensitive organelle in rat liver. Possible linkage to the plasma membrane through the actin microfilaments.

Authors: M F Rossier; G S Bird; J W Putney
Journal: Biochem J Date: 1991-03-15 Impact factor: 3.857

9. Isomers of inositol trisphosphate in exocrine pancreas.

Authors: J E Merritt; C W Taylor; R P Rubin; J W Putney
Journal: Biochem J Date: 1986-09-15 Impact factor: 3.857

10. Physiological localization of an agonist-sensitive pool of Ca2+ in parotid acinar cells.

Authors: J K Foskett; P J Gunter-Smith; J E Melvin; R J Turner
Journal: Proc Natl Acad Sci U S A Date: 1989-01 Impact factor: 11.205