Two-dimensional echocardiographic findings in a case of massive cardiac involvement by malignant lymphoma.

In a patient affected by malignant mediastinal lymphoma a severe congestive heart failure and the ECG pattern suggested a heart involvement. Two-dimensional echocardiography (2DE) documented the presence of abnormalities suggestive of infiltration: in particular, enormous thickening of the left ventricle, nearly absent wall motion, and "patchy" appearance of the myocardium were seen. Necropsy findings confirmed the presence of a massive lymphomatous infiltration of the heart. 2DE, by its ability to detect abnormalities consistent with heart infiltration, should provide a useful contribution in the staging of lymphomas.