Literature DB >> 3877473

A comparison of the induction characteristics of thiopentone and propofol (2,6-di-isopropyl phenol).

L T Fahy, G A van Mourik, J E Utting.   

Abstract

A study has been undertaken to compare the induction characteristics of the new intravenous anaesthetic agent 2,6 di-isopropyl phenol, newly prepared in a lipid emulsion (propofol) with those of thiopentone. Despite a significantly higher incidence of pain on injection and spontaneous movement, the new agent was felt to perform comparably to thiopentone as an induction agent. Unfortunately, propofol caused decreases in blood pressure which were significantly greater than those seen after thiopentone. This feature may prove to be a considerable hurdle to the general acceptance of propofol.

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Year:  1985        PMID: 3877473     DOI: 10.1111/j.1365-2044.1985.tb10546.x

Source DB:  PubMed          Journal:  Anaesthesia        ISSN: 0003-2409            Impact factor:   6.955


  8 in total

Review 1.  Acute pancreatitis after single-dose exposure to propofol: a case report and review of literature.

Authors:  Qaiser Jawaid; Michael E Presti; Brent A Neuschwander-Tetri; Frank R Burton
Journal:  Dig Dis Sci       Date:  2002-03       Impact factor: 3.199

2.  Arterial baroreflex attenuation during and after continuous propofol infusion.

Authors:  Y Kamijo; H Goto; K Nakazawa; K T Benson; K Arakawa
Journal:  Can J Anaesth       Date:  1992-11       Impact factor: 5.063

3.  Laryngeal mask airway with spontaneous breathing.

Authors:  T Kitajima; M Harmer; M Rosen
Journal:  J Anesth       Date:  1992-01       Impact factor: 2.078

4.  Hemodynamic responses with different dose of ketamine and propofol in day care gynecological surgeries.

Authors:  Kamakshi Garg; Gurpreeti Grewal; Anju Grewal; Avtar Singh; Atul Mishra; Amandeep Singh Nar; Ashvind Bawa
Journal:  J Clin Diagn Res       Date:  2013-11-10

5.  Anaesthesia for cardioversion: a comparison of propofol and thiopentone.

Authors:  M Valtonen; J Kanto; J Klossner
Journal:  Can J Anaesth       Date:  1988-09       Impact factor: 5.063

Review 6.  New intravenous anaesthetics and neuromuscular blocking drugs. A review of their properties and clinical use.

Authors:  C S Reilly; W S Nimmo
Journal:  Drugs       Date:  1987-07       Impact factor: 9.546

Review 7.  Propofol. A review of its pharmacodynamic and pharmacokinetic properties and use as an intravenous anaesthetic.

Authors:  M S Langley; R C Heel
Journal:  Drugs       Date:  1988-04       Impact factor: 9.546

8.  Propofol anaesthesia in paediatric ambulatory patients: a comparison with thiopentone and halothane.

Authors:  R S Hannallah; J T Britton; P G Schafer; R I Patel; J M Norden
Journal:  Can J Anaesth       Date:  1994-01       Impact factor: 5.063

  8 in total

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