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Literature DB >> 3877142

Differential requirements for the induction of interleukin 2 responsiveness in L3T4+ and Lyt-2+ T cell subsets.

F Erard, M Nabholz, A Dupuy-D'Angeac, H R MacDonald.

Abstract

Minimal requirements for the induction of interleukin 2 (IL-2) responsiveness in purified subsets of murine T lymphocytes have been investigated. Whereas Lyt-2+ cells could be induced to IL-2-dependent growth by lectin, phorbol ester, or calcium ionophore, none of these stimuli was by itself sufficient for L3T4+ cells. The latter cells could, however, be induced to respond to IL-2 by combinations of lectin plus phorbol ester or ionophore plus phorbol ester (but not lectin plus ionophore). Under optimal conditions, growth of L3T4+ cells (like Lyt-2+ cells) was independent of accessory cells and cell-cell contact.

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Year: 1985 PMID： 3877142 PMCID： PMC2187921 DOI： 10.1084/jem.162.5.1738

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

11 in total

1. The murine IL 2 receptor. III. Cellular requirements for the induction of IL 2 receptor expression on T cell subpopulations.

Authors: T R Malek; J A Schmidt; E M Shevach
Journal: J Immunol Date: 1985-04 Impact factor: 5.422

2. Stimulator cell requirements for allospecific T cell subsets: specialized accessory cells are required to activate helper but not cytolytic T lymphocyte precursors.

Authors: A A Czitrom; G H Sunshine; T Reme; R Ceredig; A L Glasebrook; A Kelso; H R MacDonald
Journal: J Immunol Date: 1983-02 Impact factor: 5.422

3. Con A-induced TCGF-reactivity is selectively acquired by Lyt-2-positive T cell precursors.

Authors: M Gullberg; E L Larsson
Journal: J Immunol Date: 1983-07 Impact factor: 5.422

4. Quantitative studies on concanavalin A-induced, TCGF-reactive T cells. I. Correlation between proliferation and lectin-dependent cytolytic activity.

Authors: E L Larsson; K F Lindahl; J Langhorne; A Coutinho
Journal: J Immunol Date: 1981-09 Impact factor: 5.422

5. Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis.

Authors: C Taswell
Journal: J Immunol Date: 1981-04 Impact factor: 5.422

6. The replacement of monocytes and interleukin-1 by phorbol ester in lectin-induced proliferation of human thymocytes and T cells.

Authors: J E de Vries; F A Vyth-Dreese; R van der Hulst; P Sminia; C G Figdor; W S Bont; H Spits
Journal: Immunobiology Date: 1982 Impact factor: 3.144

7. Antigen stimulation of cytolytic T lymphocyte precursors: minimal requirements for growth and acquisition of cytolytic activity.

Authors: F Erard; M Nabholz; H R MacDonald
Journal: Eur J Immunol Date: 1985-08 Impact factor: 5.532

8. Interleukin 2 is both necessary and sufficient for the growth and differentiation of lectin-stimulated cytolytic T lymphocyte precursors.

Authors: F Erard; P Corthesy; M Nabholz; J W Lowenthal; P Zaech; G Plaetinck; H R MacDonald
Journal: J Immunol Date: 1985-03 Impact factor: 5.422

9. Mutant EL-4 thymoma cells polyclonally activate murine and human B cells via direct cell interaction.

Authors: R H Zubler; F Erard; R K Lees; M Van Laer; C Mingari; L Moretta; H R MacDonald
Journal: J Immunol Date: 1985-06 Impact factor: 5.422

10. Early steps of lymphocyte activation bypassed by synergy between calcium ionophores and phorbol ester.

Authors: A Truneh; F Albert; P Golstein; A M Schmitt-Verhulst
Journal: Nature Date: 1985 Jan 24-30 Impact factor: 49.962

12 in total

1. Appearance of granule-associated molecules during activation of cytolytic T-lymphocyte precursors by defined stimuli.

Authors: J A Garcia-Sanz; F Velotti; H R MacDonald; D Masson; J Tschopp; M Nabholz
Journal: Immunology Date: 1988-05 Impact factor: 7.397

2. Autocrine regulation of T-lymphocyte proliferation: differential induction of IL-2 and IL-2 receptor.

Authors: D A Cantrell; M K Collins; M J Crumpton
Journal: Immunology Date: 1988-11 Impact factor: 7.397

3. Acquisition of cell-mediated immunity to Leishmania. I. Primary T-cell activation detected by IL-2 receptor expression.

Authors: P M Kaye
Journal: Immunology Date: 1987-07 Impact factor: 7.397

4. Role of CD4 molecule in the induction of interleukin 2 and interleukin 2 receptor in class II major histocompatibility complex-restricted antigen-specific T helper clones. T cell receptor/CD3 complex transmits CD4-dependent and CD4-independent signals.

Authors: N Oyaizu; N Chirmule; S Pahwa
Journal: J Clin Invest Date: 1992-06 Impact factor: 14.808

5. Lethal vaccinia infection in cyclophosphamide-suppressed mice is associated with decreased expression of Thy-1, Lyt-2 and L3T4 and diminished IL-2 production in surviving T cells.

Authors: Z Tabi; J E Allan; R Ceredig; P C Doherty
Journal: Immunology Date: 1988-03 Impact factor: 7.397

6. Phenotypic analysis of the inflammatory exudate in murine lymphocytic choriomeningitis.

Authors: R Ceredig; J E Allan; Z Tabi; F Lynch; P C Doherty
Journal: J Exp Med Date: 1987-06-01 Impact factor: 14.307

7. Binding and internalization of interleukin 1 by T cells. Direct evidence for high- and low-affinity classes of interleukin 1 receptor.

Authors: J W Lowenthal; H R MacDonald
Journal: J Exp Med Date: 1986-10-01 Impact factor: 14.307

8. B cell-stimulatory factor 1 (BSF-1) promotes growth of helper T cell lines.

Authors: R Fernandez-Botran; P H Krammer; T Diamantstein; J W Uhr; E S Vitetta
Journal: J Exp Med Date: 1986-08-01 Impact factor: 14.307

9. The requirement for lymphocyte function-associated antigen 1 in homotypic leukocyte adhesion stimulated by phorbol ester.

Authors: R Rothlein; T A Springer
Journal: J Exp Med Date: 1986-05-01 Impact factor: 14.307

10. T cell antigen receptor expression in athymic (nu/nu) mice. Evidence for an oligoclonal beta chain repertoire.

Authors: H R MacDonald; R K Lees; C Bron; B Sordat; G Miescher
Journal: J Exp Med Date: 1987-07-01 Impact factor: 14.307