Literature DB >> 3877117

Enzyme-linked immunosorbent assay to monitor colorectal carcinoma patients treated with a monoclonal antibody (17-1A).

C Curtet, C Maurel, J Y Douillard, B Le Mevel, M Kremer, P Sai, J F Chatal.   

Abstract

An enzyme-linked immunosorbent assay (ELISA) was compared to a radioimmunoassay (RIA) for the detection and quantification of mouse monoclonal antibody MoAb 17-1A and for measurement of the host response (i.e. anti-mouse immunoglobulin in sera from patients receiving immunotherapy with MoAb 17-1A. Comparable sensitivity and reproducibility were noted with RIA and ELISA but ELISA was more rapid to perform than RIA. Thus quantitative ELISA compared favorably with the RIA for MoAb detection.

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Year:  1985        PMID: 3877117     DOI: 10.1016/0022-1759(85)90072-9

Source DB:  PubMed          Journal:  J Immunol Methods        ISSN: 0022-1759            Impact factor:   2.303


  1 in total

1.  Radioimmunodetection of cancer of gastrointestinal tract and liver metastasis with I-131 anti-CEA and I-131 anti-CA19-9 monoclonal antibody cocktail (IMACIS-1).

Authors:  Y Naruki; Y Urita; Y Miyachi; S Otsuka; M Noguchi; T Kogure; Y Sasaki
Journal:  Ann Nucl Med       Date:  1994-08       Impact factor: 2.668

  1 in total

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