Literature DB >> 3876081

HLA antigens and toxic reactions to sodium aurothiopropanol sulphonate and D-penicillamine in patients with rheumatoid arthritis.

P Perrier, C Raffoux, P Thomas, J N Tamisier, M Busson, A Gaucher, F Streiff.   

Abstract

One hundred and forty-one patients with rheumatoid arthritis treated with aurothiopropanol sulphonate or D-penicillamine, or both were examined for HLA antigens to investigate the genetic influence on the occurrence of different adverse reactions during therapy. All 13 patients possessing HLA-DR3 had toxic reactions. The relative risk for DR3 positives of developing skin eruptions or proteinuria was calculated to be 10.5 times and seven times respectively that of DR3 negatives. The incidence of DR7 antigen in 94 patients with toxic reactions was significantly decreased (11% compared with 28% in controls) suggesting a protective role for this antigen.

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Year:  1985        PMID： 3876081      PMCID： PMC1001721          DOI： 10.1136/ard.44.9.621

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN： 0003-4967            Impact factor:   19.103


  15 in total

1.  HLA system and side effects of gold salts and D-penicillamine treatment of rheumatoid arthritis.

Authors:  T Bardin; A Dryll; N Debeyre; A Ryckewaert; L Legrand; A Marcelli; J Dausset
Journal:  Ann Rheum Dis       Date:  1982-12       Impact factor: 19.103

2.  Association of HLA antigens, toxic reactions and therapeutic response to auranofin and aurothioglucose in patients with rheumatoid arthritis.

Authors:  P L van Riel; P Reekers; L B van de Putte; F W Gribnau
Journal:  Tissue Antigens       Date:  1983-09

3.  [The HLA-DR determinants in chronic inflammatory rheumatism].

Authors:  G Chalès; R Fauchet; Y Pawlotsky; M Gueguen; J Coutard; A Duval; P Pittie
Journal:  Rev Rhum Mal Osteoartic       Date:  1983-06

4.  Association of the B-cell alloantigen DRw4 with rheumatoid arthritis.

Authors:  P Stastny
Journal:  N Engl J Med       Date:  1978-04-20       Impact factor: 91.245

5.  Gold therapy in rheumatoid arthritis.

Authors:  F L Majoos; P Klemp; O L Meyers; B Briggs
Journal:  S Afr Med J       Date:  1981-06-27

6.  Genetic basis of rheumatoid disease: HLA antigens, disease manifestations, and toxic reactions to drugs.

Authors:  G S Panayi; P Wooley; J R Batchelor
Journal:  Br Med J       Date:  1978-11-11

7.  Gold-induced thrombocytopenia. A clinical and immunogenetic study of twenty-three patients.

Authors:  J S Coblyn; M Weinblatt; D Holdsworth; D Glass
Journal:  Ann Intern Med       Date:  1981-08       Impact factor: 25.391

8.  Association of HLA-DRw4 with rheumatoid arthritis in black and white patients.

Authors:  R W Karr; G E Rodey; T Lee; B D Schwartz
Journal:  Arthritis Rheum       Date:  1980-11

9.  HLA DR antigens and gold toxicity.

Authors:  J T Gran; G Husby; E Thorsby
Journal:  Ann Rheum Dis       Date:  1983-02       Impact factor: 19.103

10.  HLA-DR antigens and toxic reaction to sodium aurothiomalate and D-penicillamine in patients with rheumatoid arthritis.

Authors:  P H Wooley; J Griffin; G S Panayi; J R Batchelor; K I Welsh; T J Gibson
Journal:  N Engl J Med       Date:  1980-08-07       Impact factor: 91.245
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  9 in total

Review 1.  Immunotoxicology: suppressive and stimulatory effects of drugs and environmental chemicals on the immune system. A discussion.

Authors:  E Gleichmann; I Kimber; I F Purchase
Journal:  Arch Toxicol       Date:  1989       Impact factor: 5.153

Review 2.  Drug toxicity.

Authors:  H A Bird
Journal:  Ann Rheum Dis       Date:  1990-05       Impact factor: 19.103

3.  D-penicillamine in the therapy of ankylosing spondylitis.

Authors:  K Tytman; K Bernacka; S Sierakowski
Journal:  Clin Rheumatol       Date:  1989-09       Impact factor: 2.980

4.  Disease-modifying drugs for rheumatoid arthritis. Asset or liability?

Authors:  H A Bird
Journal:  Clin Rheumatol       Date:  1987-12       Impact factor: 2.980

Review 5.  Adverse reactions with oral and parenteral gold preparations.

Authors:  E C Tozman; N L Gottlieb
Journal:  Med Toxicol       Date:  1987 May-Jun

Review 6.  Gold colitis induced by auranofin treatment of rheumatoid arthritis: case report and review of the literature.

Authors:  H E Langer; G Hartmann; G Heinemann; K Richter
Journal:  Ann Rheum Dis       Date:  1987-10       Impact factor: 19.103

Review 7.  Clinical pharmacokinetics of D-penicillamine.

Authors:  P Netter; B Bannwarth; P Péré; A Nicolas
Journal:  Clin Pharmacokinet       Date:  1987-11       Impact factor: 6.447

8.  Association between gold induced skin rash and remission in patients with rheumatoid arthritis.

Authors:  D Caspi; M Tishler; M Yaron
Journal:  Ann Rheum Dis       Date:  1989-09       Impact factor: 19.103

9.  HLA-DRB1*08:02 Is Associated with Bucillamine-Induced Proteinuria in Japanese Rheumatoid Arthritis Patients.

Authors:  Hiroshi Furukawa; Shomi Oka; Kota Shimada; Shoji Sugii; Atsushi Hashimoto; Akiko Komiya; Naoshi Fukui; Taiichiro Miyashita; Kiyoshi Migita; Akiko Suda; Shouhei Nagaoka; Naoyuki Tsuchiya; Shigeto Tohma
Journal:  Biomark Insights       Date:  2014-05-19
  9 in total

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