Literature DB >> 3875473

The place of temocillin in the treatment of hospital infections.

J D Williams, H Y Chen.   

Abstract

Infection due to Gram-negative bacteria continues to be a common problem in the hospital environment, for which a wide variety of antibiotics is available. Among Enterobacteria, resistance is expressed most commonly via beta-lactamases. Temocillin is the first penicillin to show stability to beta-lactamases of Gram-negative bacteria, therefore it is in this type of infection that the initial assessments of temocillin should be made.

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Year:  1985        PMID： 3875473     DOI： 10.2165/00003495-198500295-00051

Source DB:  PubMed          Journal:  Drugs        ISSN： 0012-6667            Impact factor:   9.546


  10 in total

1.  Monobactams--structure-activity relationships leading to SQ 26,776.

Authors:  H Breuer; C M Cimarusti; T Denzel; W H Koster; W A Slusarchyk; U D Treuner
Journal:  J Antimicrob Chemother       Date:  1981-12       Impact factor: 5.790

2.  Frequency of appearance of resistant variants to norfloxacin and nalidixic acid.

Authors:  G J Duckworth; J D Williams
Journal:  J Antimicrob Chemother       Date:  1984-05       Impact factor: 5.790

3.  National survey of antibiotic resistance in Pseudomonas aeruginosa.

Authors:  R J Williams; M A Lindridge; A A Said; D M Livermore; J D Williams
Journal:  J Antimicrob Chemother       Date:  1984-07       Impact factor: 5.790

4.  Temocillin compared to ampicillin against Haemophilus influenzae and with other penicillins against intestinal aerobic Gram-negative rods.

Authors:  H Y Chen; J D Williams
Journal:  J Antimicrob Chemother       Date:  1982-10       Impact factor: 5.790

5.  Monocyclic beta-lactam antibiotics produced by bacteria.

Authors:  R B Sykes; C M Cimarusti; D P Bonner; K Bush; D M Floyd; N H Georgopapadakou; W M Koster; W C Liu; W L Parker; P A Principe; M L Rathnum; W A Slusarchyk; W H Trejo; J S Wells
Journal:  Nature       Date:  1981-06-11       Impact factor: 49.962

6.  Mechanisms of beta-lactam resistance in British isolates of Pseudomonas aeruginosa.

Authors:  R J Williams; D M Livermore; M A Lindridge; A A Said; J D Williams
Journal:  J Med Microbiol       Date:  1984-06       Impact factor: 2.472

7.  BRL 17421, a novel beta-lactam antibiotic, highly resistant to beta-lactamases, giving high and prolonged serum levels in humans.

Authors:  B Slocombe; M J Basker; P H Bentley; J P Clayton; M Cole; K R Comber; R A Dixon; R A Edmondson; D Jackson; D J Merrikin; R Sutherland
Journal:  Antimicrob Agents Chemother       Date:  1981-07       Impact factor: 5.191

8.  Antibacterial activity and beta-lactamase stability of temocillin.

Authors:  K Jules; H C Neu
Journal:  Antimicrob Agents Chemother       Date:  1982-09       Impact factor: 5.191

9.  In vitro antibacterial activity of AM-715, a new nalidixic acid analog.

Authors:  A Ito; K Hirai; M Inoue; H Koga; S Suzue; T Irikura; S Mitsuhashi
Journal:  Antimicrob Agents Chemother       Date:  1980-02       Impact factor: 5.191

10.  MK0787 (N-formimidoyl thienamycin): evaluation of in vitro and in vivo activities.

Authors:  H Kropp; J G Sundelof; J S Kahan; F M Kahan; J Birnbaum
Journal:  Antimicrob Agents Chemother       Date:  1980-06       Impact factor: 5.191
  10 in total
  1 in total

Review 1.  Temocillin: Applications in Antimicrobial Stewardship as a Potential Carbapenem-Sparing Antibiotic.

Authors:  Tommaso Lupia; Ilaria De Benedetto; Giacomo Stroffolini; Stefano Di Bella; Simone Mornese Pinna; Verena Zerbato; Barbara Rizzello; Roberta Bosio; Nour Shbaklo; Silvia Corcione; Francesco Giuseppe De Rosa
Journal:  Antibiotics (Basel)       Date:  2022-04-07
  1 in total

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