Literature DB >> 3875312

Studies with temocillin in a hamster model of antibiotic-associated colitis.

R J Boon, A S Beale.   

Abstract

Hamsters given the new penicillin temocillin, either orally or by injection, did not develop antibiotic-associated colitis, whereas animals given the control antibiotics cefoxitin or clindamycin developed the disease, which is characterized by marked hemorrhagic cecitis and high cecal levels of Clostridium difficile cytotoxin.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 3875312      PMCID： PMC180203          DOI： 10.1128/AAC.27.6.980

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  3 in total

1.  BRL 17421, a novel beta-lactam antibiotic, highly resistant to beta-lactamases, giving high and prolonged serum levels in humans.

Authors:  B Slocombe; M J Basker; P H Bentley; J P Clayton; M Cole; K R Comber; R A Dixon; R A Edmondson; D Jackson; D J Merrikin; R Sutherland
Journal:  Antimicrob Agents Chemother       Date:  1981-07       Impact factor: 5.191

2.  Evaluation of eight cephalosporins in hamster colitis model.

Authors:  J R Ebright; R Fekety; J Silva; K H Wilson
Journal:  Antimicrob Agents Chemother       Date:  1981-06       Impact factor: 5.191

3.  Suppression of Clostridium difficile by normal hamster cecal flora and prevention of antibiotic-associated cecitis.

Authors:  K H Wilson; J Silva; F R Fekety
Journal:  Infect Immun       Date:  1981-11       Impact factor: 3.441
  3 in total
  3 in total

1.  ESBLs: A Clear and Present Danger?

Authors:  Rishi H-P Dhillon; John Clark
Journal:  Crit Care Res Pract       Date:  2011-06-06

2.  Amoxicillin plus temocillin as an alternative empiric therapy for the treatment of severe hospital-acquired pneumonia: results from a retrospective audit.

Authors:  H Habayeb; B Sajin; K Patel; C Grundy; A Al-Dujaili; S Van de Velde
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2015-05-19       Impact factor: 3.267

Review 3.  Temocillin: Applications in Antimicrobial Stewardship as a Potential Carbapenem-Sparing Antibiotic.

Authors:  Tommaso Lupia; Ilaria De Benedetto; Giacomo Stroffolini; Stefano Di Bella; Simone Mornese Pinna; Verena Zerbato; Barbara Rizzello; Roberta Bosio; Nour Shbaklo; Silvia Corcione; Francesco Giuseppe De Rosa
Journal:  Antibiotics (Basel)       Date:  2022-04-07
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.