Literature DB >> 387385

Isolation and characterization of somatostatin from anglerfish pancreatic islet.

B D Noe, J Spiess, J E Rivier, W Vale.   

Abstract

Somatostatin was purified from anglerfish pancreatic islets using acetic acid extraction, gel filtration (Bio-Gel P-10), ion exchange chromatography (CM Bio-Gel A), and reversed phase high pressure liquid chromatography. The resulting peptide was characterized by RIA, bioassay, and determination of amino acid composition. Anglerfish islet somatostatin was found to possess an amino acid composition and immunological and biological activities equivalent to synthetic somatostatin. Sequence analyses revealed that the primary structure was H-Ala-Gly-cyclo-[Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys]-OH. These results demonstrate that anglerfish islet somatostatin has the same primary structure as somatostatin from all other sources characterized to date.

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Year:  1979        PMID： 387385     DOI： 10.1210/endo-105-6-1410

Source DB:  PubMed          Journal:  Endocrinology        ISSN： 0013-7227            Impact factor:   4.736


  12 in total

Review 1.  Precursors to regulatory peptides: their proteolytic processing.

Authors:  P C Andrews; K Brayton; J E Dixon
Journal:  Experientia       Date:  1987-07-15

2.  Prosomatostatin-specific antigen in rat brain: localization by immunocytochemical staining with an antiserum to a synthetic sequence of preprosomatostatin.

Authors:  R M Lechan; R H Goodman; M Rosenblatt; S Reichlin; J F Habener
Journal:  Proc Natl Acad Sci U S A       Date:  1983-05       Impact factor: 11.205

3.  Primary structure of ovine hypothalamic somatostatin-28 and somatostatin-25.

Authors:  F Esch; P Böhlen; N Ling; R Benoit; P Brazeau; R Guillemin
Journal:  Proc Natl Acad Sci U S A       Date:  1980-11       Impact factor: 11.205

Review 4.  Secretion of somatostatin from the normal and diabetic pancreas. Studies in vitro.

Authors:  K Hermansen
Journal:  Diabetologia       Date:  1980       Impact factor: 10.122

5.  Processing of an anglerfish somatostatin precursor to a hydroxylysine-containing somatostatin 28.

Authors:  J Spiess; B D Noe
Journal:  Proc Natl Acad Sci U S A       Date:  1985-01       Impact factor: 11.205

6.  Bombesin-, gastrin/CCK-, 5-hydroxytryptamine-, neurotensin-, somatostatin-, and VIP-like immunoreactivity and catecholamine fluorescence in the gut of the elasmobranch, Squalus acanthias.

Authors:  S Holmgren; S Nilsson
Journal:  Cell Tissue Res       Date:  1983       Impact factor: 5.249

7.  Sequence analysis of a cDNA coding for a pancreatic precursor to somatostatin.

Authors:  W L Taylor; K J Collier; R J Deschenes; H L Weith; J E Dixon
Journal:  Proc Natl Acad Sci U S A       Date:  1981-11       Impact factor: 11.205

8.  VIP-, substance P-, gastrin/CCK-, bombesin-, somatostatin- and glucagon-like immunoreactivities in the gut of the rainbow trout, Salmo gairdneri.

Authors:  S Holmgren; C Vaillant; R Dimaline
Journal:  Cell Tissue Res       Date:  1982       Impact factor: 5.249

9.  Characterization of a somatostatin-28 containing the (Tyr-7, Gly-10) derivative of somatostatin-14: a terminal active product of prosomatostatin II processing in anglerfish pancreatic islets.

Authors:  A Morel; P Gluschankof; S Gomez; V Fafeur; P Cohen
Journal:  Proc Natl Acad Sci U S A       Date:  1984-11       Impact factor: 11.205

10.  Nucleotide sequence of a cloned structural gene coding for a precursor of pancreatic somatostatin.

Authors:  R H Goodman; J W Jacobs; W W Chin; P K Lund; P C Dee; J F Habener
Journal:  Proc Natl Acad Sci U S A       Date:  1980-10       Impact factor: 11.205
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