Literature DB >> 3873352

Natural killer-like activity in human cultured lymphoid cells propagated in the presence of interleukin-2: acquired resistance to prostaglandin E2- or dexamethasone-mediated suppression.

H Suzuki, N Yamashita, M Sato, M Iwata, M Maruyama, S Yano.   

Abstract

The cytotoxic activity of human peripheral blood lymphocytes against the natural killer-sensitive target K562 was suppressed both by prostaglandin E2 and dexamethasone. On the other hand, cultured lymphoid cells propagated in the presence of interleukin-2 showed strong cytotoxic reactivity against K562 targets, and were resistant to prostaglandin E2- or dexamethasone-mediated suppression.

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Year:  1985        PMID： 3873352     DOI： 10.1007/bf02007711

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  13 in total

1.  Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome.

Authors:  C B Lozzio; B B Lozzio
Journal:  Blood       Date:  1975-03       Impact factor: 22.113

Review 2.  Natural cell-mediated immunity.

Authors:  R B Herberman; H T Holden
Journal:  Adv Cancer Res       Date:  1978       Impact factor: 6.242

3.  Immune responses in vitro. I. Culture conditions for antibody synthesis.

Authors:  R E Click; L Benck; B J Alter
Journal:  Cell Immunol       Date:  1972-02       Impact factor: 4.868

4.  Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

Authors:  A Böyum
Journal:  Scand J Clin Lab Invest Suppl       Date:  1968

5.  Disappearance of the NK effect after explantation of lymphocytes and generation of similar nonspecific cytotoxicity correlated to the level of blastogenesis in activated cultures.

Authors:  M G Masucci; E Klein; S Argov
Journal:  J Immunol       Date:  1980-05       Impact factor: 5.422

6.  Suppression of the natural killer cell activity of murine spleen cell cultures by dexamethasone (41489).

Authors:  W I Cox; N J Holbrook; R J Grasso; S Specter; H Friedman
Journal:  Proc Soc Exp Biol Med       Date:  1982-11

7.  Genetic influences on the augmentation of natural killer (NK) cells during murine cytomegalovirus infection: correlation with patterns of resistance.

Authors:  G J Bancroft; G R Shellam; J E Chalmer
Journal:  J Immunol       Date:  1981-03       Impact factor: 5.422

8.  Natural cell-mediated cytotoxicity in vitro and inhibition of tumor growth in vivo by murine lymphoid cells cultured with T cell growth factor (TCGF).

Authors:  E Kedar; B L Ikejiri; E Gorelik; R B Herbermann
Journal:  Cancer Immunol Immunother       Date:  1982       Impact factor: 6.968

9.  Antitumor reactivity in vitro and in vivo of lymphocytes from normal donors and cancer patients propagated in culture with T cell growth factor (TCGF).

Authors:  E Kedar; B L Ikejiri; T Timonen; G D Bonnard; J Reid; N J Navarro; B Sredni; R B Herberman
Journal:  Eur J Cancer Clin Oncol       Date:  1983-06

10.  Regulation of human natural killing. II. Protective effect of interferon on NK cells from suppression by PGE2.

Authors:  K H Leung; H S Koren
Journal:  J Immunol       Date:  1982-10       Impact factor: 5.422
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  1 in total

Review 1.  Immunotherapy for malignant glioma using human recombinant interleukin-2 and activated autologous lymphocytes. A review of pre-clinical and clinical investigations.

Authors:  R E Merchant; M D Ellison; H F Young
Journal:  J Neurooncol       Date:  1990-04       Impact factor: 4.130
  1 in total

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