| Literature DB >> 3872661 |
K Naruo, S Hinuma, K Kato, M Koyama, H Tada, O Shiho, K Tsukamoto.
Abstract
We compared the biological properties of the purified recombinant human IL-2 derived from E. coli with those of purified natural IL-2. Both had almost the same specific in vitro activities on a weight basis to support long-term proliferation of IL-2 dependent human peripheral blood lymphocytes, a mouse killer T cell line, and a mouse natural killer cell line; induce killer cells in normal mouse spleen cells; and induce antibody forming cells in nude mouse spleen cells. No differences in these biological activities were found between two forms of natural IL-2 that were separable by reverse phase high performance liquid chromatography.Entities:
Mesh：
Substances：
Year: 1985 PMID： 3872661 DOI： 10.1016/0006-291x(85)91672-9
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575