Literature DB >> 3872491

Composite tissue (limb) allografts in rats. II. Indefinite survival using low-dose cyclosporine.

K S Black, C W Hewitt, L A Fraser, E B Howard, D C Martin, B M Achauer, D W Furnas.   

Abstract

Cyclosporine has reawakened interest in transplantation of peripheral composite tissue allografts (CTA) of skin, muscle, bone, vessel, and nerves. The purpose of this study was to examine whether cyclosporine could produce indefinite survival of CTA. Two groups of LEW recipients of LBN limb transplants were given different long-term treatments of cyclosporine. Tolerance was achieved in many of the animals. Several possibilities for the mechanism of this tolerance are discussed.

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Year:  1985        PMID: 3872491     DOI: 10.1097/00007890-198504000-00005

Source DB:  PubMed          Journal:  Transplantation        ISSN: 0041-1337            Impact factor:   4.939


  6 in total

1.  Nerve allotransplantation as it pertains to composite tissue transplantation.

Authors:  Amy M Moore; Wilson Z Ray; Kristofer E Chenard; Thomas Tung; Susan E Mackinnon
Journal:  Hand (N Y)       Date:  2009-03-21

2.  Successful long-term storage of rat limbs. The use of simple immersion in Euro-Collins solution.

Authors:  K Arai; T Hotokebuchi; H Miyahara; M Mohtai; H K Kitadai; Y Sugioka; N Kaibara
Journal:  Int Orthop       Date:  1993-12       Impact factor: 3.075

3.  An old friendship revisited: plastic surgery and transplantation.

Authors:  B A Shuster; L A Hoffman
Journal:  Aesthetic Plast Surg       Date:  1994       Impact factor: 2.326

4.  Orthotopic homotransplantation of vascularized composite mandibular tissue in rabbits immunosuppressed with cyclosporine A.

Authors:  C F He; S S Xia; J Z Chen
Journal:  J Tongji Med Univ       Date:  1990

5.  The characteristics of acute rejection after limb allotransplantation in rats--an experimental study.

Authors:  Hao Kang; Guangxiang Hong; Fabin Wang; Zhenbing Chen; Qishun Huang; Yuxiong Weng
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2003

6.  Chimerism-based experimental models for tolerance induction in vascularized composite allografts: Cleveland clinic research experience.

Authors:  Maria Siemionow; Aleksandra Klimczak
Journal:  Clin Dev Immunol       Date:  2013-03-14
  6 in total

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