Literature DB >> 3868360

The formation of glutathione-chromium complexes and their possible role in chromium disposition.

H J Wiegand, H Ottenwälder, H M Bolt.   

Abstract

The reduction of Cr(VI) to Cr(III) by glutathione (GSH) in vitro resulted in the formation of two different GSH-chromium complexes with an approximate molecular-weight of 10,000 and 5000, respectively. Both complexes exhibited strong fluorescence. The molar ratio between oxidized glutathione (GSSG) and chromium was calculated by determining the chromium content of the two isolated complex species by flameless Atomic Absorption Spectrometry (AAS).

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Year:  1985        PMID: 3868360     DOI: 10.1007/978-3-642-69928-3_61

Source DB:  PubMed          Journal:  Arch Toxicol Suppl        ISSN: 0171-9750


  2 in total

1.  Reduction of hexavalent chromium by ascorbic acid in rat lung lavage fluid.

Authors:  Y Suzuki
Journal:  Arch Toxicol       Date:  1988       Impact factor: 5.153

2.  The role of glutathione in the acute nephrotoxicity of sodium dichromate.

Authors:  K J Na; S Y Jeong; C H Lim
Journal:  Arch Toxicol       Date:  1992       Impact factor: 5.153

  2 in total

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