| Literature DB >> 3865623 |
Abstract
The hypothesis is put forward that the low frequency of A and high frequency of O blood group genes in the Icelandic human population is the result of a selective disadvantage of A during severe smallpox epidemics. The hypothesis is supported by data from India in 1965-6, which show a marked selective effect of a smallpox epidemic against the phenotypes A and AB (Vogel & Chakravartti, 1971). The conclusion is drawn that the present-day ABO blood group gene frequencies of the Icelandic population should be used with reservation as markers in the study of the origin of the Icelanders.Entities:
Mesh：
Substances：
Year: 1985 PMID： 3865623 DOI： 10.1111/j.1469-1809.1985.tb01703.x
Source DB: PubMed Journal: Ann Hum Genet ISSN： 0003-4800 Impact factor: 1.670