Osteogenic sarcoma in pregnant women. Prognosis, therapeutic implications, and literature review.

This study of 18 pregnant women with concomitant osteogenic sarcoma of bone analyzes the important assertion whether this sarcoma and pregnancy have an adverse interaction. For comparison we matched the pregnant osteogenic sarcoma patients with nonpregnant women with the same skeletal tumor location and histologic appearance as well as similar age distribution. There was no worsening of prognosis of pregnant osteogenic sarcoma patients, and neither the pregnancy nor the disease appeared to act adversely toward the other. The 18 pregnant women with osteogenic sarcoma fared no better (nor worse) than the nonpregnant women with osteogenic sarcoma.