| Literature DB >> 3862660 |
I D Farrell, J Barker, P L Chiodini, J G Hutchison, A M Geddes.
Abstract
An in-vitro assessment of the activity of imipenem, a new carbapenem beta-lactam antibiotic, was undertaken on isolates of Legionella pneumophila. The minimum inhibitory concentrations of imipenem were in the range 0.03 to 0.25 mg/l and turbidimetric studies showed that imipenem had a marked bactericidal effect which was more pronounced than that seen with either rifampicin or erythromycin. Two patients with legionella pneumonia were successfully treated with imipenem as part of a clinical trial of the drug.Entities:
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Year: 1985 PMID： 3862660 DOI： 10.1093/jac/16.1.61
Source DB: PubMed Journal: J Antimicrob Chemother ISSN： 0305-7453 Impact factor: 5.790