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Literature DB >> 3861473

Ulcerative colitis and HLA phenotype.

M Cottone, M Bunce, C J Taylor, A Ting, D P Jewell.

Abstract

The distribution of HLA A, B, C, DR antigens was investigated in a British population with ulcerative colitis. Fifty six patients were typed for HLA, A, B, C and 46 additionally for DR. No association was found between the HLA phenotype and the presence or absence of ulcerative colitis. Serum from 52 patients was tested for the presence of the anticolon antibody. There was no relation between the presence of the antibody and the HLA phenotype. Finally, no correlation was found between the HLA phenotypes, the age of onset of the disease, the extent and the clinical course.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 1985 PMID： 3861473 PMCID： PMC1432843 DOI： 10.1136/gut.26.9.952

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

10 in total

Ulcerative colitis and HLA phenotype.

1. Progress report. Familial inflammatory bowel disease--heredity or environment?

2. Histocompatibility antigens in patients with inflammatory-bowel disease.

3. Immunological studies in ulcerative colitis. V. Family studies.

4. Serotyping for homotransplantation. 18. Refinement of microdroplet lymphocyte cytotoxicity test.

5. HL-A frequencies in Crohn's disease and ulcerative colitis.

Review 6. Microdroplet testing for HLA-A, -B, -C, and -D antigens. The Phillip Levine Award Lecture.

7. HLA antigens in ulcerative colitis and Crohn's disease in Israel.

8. HLA antigens in inflammatory bowel disease.

9. Human leucocyte antigens in Crohn's disease and ulcerative colitis.

10. Association of the human lymphocyte-DR2 antigen with Japanese ulcerative colitis.

1. HLA-DR and -DQ phenotypes in inflammatory bowel disease: a meta-analysis.

2. Inflammatory bowel disease: definition, epidemiology, etiologic aspects, and immunogenetic studies.

3. Effects of family history on inflammatory bowel disease characteristics in Japanese patients.

Review 4. Are the inflammatory bowel diseases autoimmune disorders?

5. Inflammatory bowel disease in Korea: epidemiological, genomic, clinical, and therapeutic characteristics.

6. Genetics of inflammatory bowel disease.

7. Ulcerative colitis and sarcoidosis.

8. Transient IgA and IgM deficiencies are frequent in children with ulcerative colitis.

Review 9. Pulmonary-intestinal cross-talk in mucosal inflammatory disease.

10. Familial aggregation of inflammatory bowel disease in patients with ulcerative colitis.