Literature DB >> 3861204

Production of leukemic blast growth factor by a human bladder carcinoma cell line.

T Hoang, E A McCulloch.   

Abstract

Circulating blast cells from the peripheral blood of acute myeloblastic leukemia patients include a subpopulation capable of colony formation in the presence of phytohemagglutinin-stimulated leukocyte-conditioned medium (PHA-LCM). We describe the complete replacement in the blast assay of PHA-LCM by conditioned medium from a human bladder carcinoma cell line, HTB9. Both conditioned media contain a stimulator of blast cell growth that elutes as a single peak from a Sephadex G100 column with an apparent molecular weight of 30,000. It is shown that this leukemic blast growth factor is distinct from erythroid-potentiating activity (EPA) and possibly granulocyte macrophage colony-stimulating factor.

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Year:  1985        PMID： 3861204

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  8 in total

1.  Modulation of gene expression in multiple hematopoietic cell lineages following retroviral vector gene transfer.

Authors:  M C Magli; J E Dick; D Huszar; A Bernstein; R A Phillips
Journal:  Proc Natl Acad Sci U S A       Date:  1987-02       Impact factor: 11.205

2.  The role of CFU-GEMM in human hemopoiesis.

Authors:  H A Messner
Journal:  Blut       Date:  1986-10

3.  Triple combination of retinoic acid plus actinomycin D plus dimethylformamide induces differentiation of human acute myeloid leukaemic blasts in primary culture.

Authors:  H T Hassan; J Rees
Journal:  Cancer Chemother Pharmacol       Date:  1990       Impact factor: 3.333

4.  Expression of the p53 oncogene in acute myeloblastic leukemia.

Authors:  L J Smith; E A McCulloch; S Benchimol
Journal:  J Exp Med       Date:  1986-09-01       Impact factor: 14.307

5.  T cell receptor and immunoglobulin gene rearrangements in acute myeloblastic leukemia.

Authors:  G Y Cheng; M D Minden; B Toyonaga; T W Mak; E A McCulloch
Journal:  J Exp Med       Date:  1986-02-01       Impact factor: 14.307

6.  Wild-type p53 is required for apoptosis induced by growth factor deprivation in factor-dependent leukaemic cells.

Authors:  Y M Zhu; D A Bradbury; N H Russell
Journal:  Br J Cancer       Date:  1994-03       Impact factor: 7.640

7.  Interleukin 1 enhances growth factor-dependent proliferation of the clonogenic cells in acute myeloblastic leukemia and of normal human primitive hemopoietic precursors.

Authors:  T Hoang; A Haman; O Goncalves; F Letendre; M Mathieu; G G Wong; S C Clark
Journal:  J Exp Med       Date:  1988-08-01       Impact factor: 14.307

8.  Effects of recombinant human granulocyte colony-stimulating factor (G-CSF) on blast progenitors from acute myeloblastic leukaemia patients.

Authors:  N Nara; I Murohashi; T Suzuki; Y Yamashita; Y Maruyama; N Aoki; S Tanikawa; Y Onozawa
Journal:  Br J Cancer       Date:  1987-07       Impact factor: 7.640
  8 in total

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