Literature DB >> 3861091

Clonal development from a progenitor with restricted differentiative expression in acute lymphoblastic leukemia.

A M Ferraris, L Canepa, L Massimo, G Dini, G Broccia, T Meloni, G Forteleoni, C Melani, G F Gaetani.   

Abstract

Three patients with acute lymphoblastic leukemia (ALL) and heterozygous for the Mediterranean variant of glucose-6-phosphate dehydrogenase (G6PD) have been investigated with the 2-deoxyglucose-6-phosphate (2dG6P) method to determine the number and type of progenitor cells in which the disease arose. A monoclonal origin was established for the lymphoblasts, while the other hemopoietic cell lines were not involved in the leukemic process.

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Year:  1985        PMID： 3861091     DOI： 10.1002/ajh.2830200111

Source DB:  PubMed          Journal:  Am J Hematol        ISSN： 0361-8609            Impact factor:   10.047


  2 in total

1.  Glucose 6-phosphate dehydrogenase deficiency and incidence of hematologic malignancy.

Authors:  A M Ferraris; G Broccia; T Meloni; G Forteleoni; G F Gaetani
Journal:  Am J Hum Genet       Date:  1988-03       Impact factor: 11.025

2.  A case of ataxia telangiectasia with unbalanced glucose 6-phosphate dehydrogenase mosaicism in the granulocytic/monocytic lineages.

Authors:  A M Ferraris; C Melani; L Canepa; T Meloni; G Forteleoni; G F Gaetani
Journal:  Am J Hum Genet       Date:  1987-01       Impact factor: 11.025
  2 in total

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