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Literature DB >> 3860876

Antiserum to lens antigens immunostains Müller glia cells in the neural retina.

A A Moscona, L Fox, J Smith, L Degenstein.

Abstract

Antiserum to a lens fraction enriched for alpha-crystallin selectively immunostains Müller glia cells in the neural retina of several vertebrate species. Also, in embryonic retina (chicken), this antiserum reacts with Müller cells and, at early stages of development, with their apparent precursors. Thus, antibodies to a lens product(s) detect a Müller glia cell marker that begins to be expressed very early in their ontogeny and can be useful in studies on differentiation, function, and pathologies of this cell type.

Entities: Disease Species

Mesh：

Substances：
Crystallins
Immune Sera

Year: 1985 PMID： 3860876 PMCID： PMC391164 DOI： 10.1073/pnas.82.16.5570

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

15 in total

1. Selective reassociation of the crystallins.

Authors: H Bloemendal; A Zweers; E L Benedetti; H Walters
Journal: Exp Eye Res Date: 1975-05 Impact factor: 3.467

2. Formation of lentoids by dissociated retinal cells of the chick embryo.

Authors: A MOSCONA
Journal: Science Date: 1957-03-29 Impact factor: 47.728

3. Biochemical and immunological studies of lentoid formation in cultures of embryonic chick neural retina and day-old chick lens epithelium.

Authors: D I De Pomerai; D J Pritchard; R M Clayton
Journal: Dev Biol Date: 1977-10-15 Impact factor: 3.582

4. Carbonic anhydrase C in the neural retina: transition from generalized to glia-specific cell localization during embryonic development.

Authors: P Linser; A A Moscona
Journal: Proc Natl Acad Sci U S A Date: 1981-11 Impact factor: 11.205

5. Four small Drosophila heat shock proteins are related to each other and to mammalian alpha-crystallin.

Authors: T D Ingolia; E A Craig
Journal: Proc Natl Acad Sci U S A Date: 1982-04 Impact factor: 11.205

6. Sequence complexity and tissue distribution of chick lens crystallin mRNAs.

Authors: J F Jackson; R M Clayton; R Williamson; I Thomson; D E Truman; D I de Pomerai
Journal: Dev Biol Date: 1978-08 Impact factor: 3.582

Review 7. Cellular metaplasia or transdifferentiation as a model for retinal cell differentiation.

Authors: T S Okada
Journal: Curr Top Dev Biol Date: 1980 Impact factor: 4.897

8. Lentoids in aggregates of embryonic neural retina cells.

Authors: A A Moscona; L Degenstein
Journal: Cell Differ Date: 1981-01

Review 9. Lens differentiation in vertebrates. A review of cellular and molecular features.

Authors: J Piatigorsky
Journal: Differentiation Date: 1981 Impact factor: 3.880

10. Induction of glutamine synthetase in embryonic neural retina: localization in Müller fibers and dependence on cell interactions.

Authors: P Linser; A A Moscona
Journal: Proc Natl Acad Sci U S A Date: 1979-12 Impact factor: 11.205

5 in total

1. Alpha-crystallin can function as a molecular chaperone.

Authors: J Horwitz
Journal: Proc Natl Acad Sci U S A Date: 1992-11-01 Impact factor: 11.205

2. The lens protein alpha A-crystallin of the blind mole rat, Spalax ehrenbergi: evolutionary change and functional constraints.

Authors: W Hendriks; J Leunissen; E Nevo; H Bloemendal; W W de Jong
Journal: Proc Natl Acad Sci U S A Date: 1987-08 Impact factor: 11.205