| Literature DB >> 3859743 |
F Bessho, H Kinumaki, M Kobayashi, H Habu, K Nakamura, S Yokota, T Tsuruo, N Kobayashi.
Abstract
Six children with refractory acute lymphocytic leukemia were treated with vincristine combined with diltiazem. In four of five children who took the drug as scheduled, a cytolytic effect was observed. One child showed massive cell destruction which caused hyperuricemic nephropathy. The only adverse effect was atrioventricular block in two children, which was completely reversible. Increased neurotoxicity was not observed in any child.Entities:
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Year: 1985 PMID： 3859743 DOI： 10.1002/mpo.2950130408
Source DB: PubMed Journal: Med Pediatr Oncol ISSN： 0098-1532