Literature DB >> 3857372

A colon cancer cell line (LIM1215) derived from a patient with inherited nonpolyposis colorectal cancer.

R H Whitehead, F A Macrae, D J St John, J Ma.   

Abstract

A new human colon cancer cell line (LIM1215) has been derived from a tumor arising in a member of a family known to have a high incidence of colorectal cancer. The tumor cell line is comprised of small pleomorphic cells that clone in liquid medium and form tumors in immunosuppressed mice. Ultrastructurally, the cells are capable of differentiation, with cells with multiple microvilli and cells resembling goblet cells being present in the one culture. The cells are pseudodiploid and contain a 13p+ marker chromosome.

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Year:  1985        PMID： 3857372

Source DB:  PubMed          Journal:  J Natl Cancer Inst        ISSN： 0027-8874            Impact factor:   13.506


  37 in total

1.  Dual-channel photobleaching FRET microscopy for improved resolution of protein association states in living cells.

Authors:  Andrew H A Clayton; Nectarios Klonis; Stephen H Cody; Edouard C Nice
Journal:  Eur Biophys J       Date:  2004-06-30       Impact factor: 1.733

2.  Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer.

Authors:  Sandra Misale; Rona Yaeger; Sebastijan Hobor; Elisa Scala; Manickam Janakiraman; David Liska; Emanuele Valtorta; Roberta Schiavo; Michela Buscarino; Giulia Siravegna; Katia Bencardino; Andrea Cercek; Chin-Tung Chen; Silvio Veronese; Carlo Zanon; Andrea Sartore-Bianchi; Marcello Gambacorta; Margherita Gallicchio; Efsevia Vakiani; Valentina Boscaro; Enzo Medico; Martin Weiser; Salvatore Siena; Federica Di Nicolantonio; David Solit; Alberto Bardelli
Journal:  Nature       Date:  2012-06-28       Impact factor: 49.962

3.  The proliferative and morphologic responses of a colon carcinoma cell line (LIM 1215) require the production of two autocrine factors.

Authors:  A M Sizeland; A W Burgess
Journal:  Mol Cell Biol       Date:  1991-08       Impact factor: 4.272

4.  Rapid and comprehensive 'shotgun' lipidome profiling of colorectal cancer cell derived exosomes.

Authors:  Todd A Lydic; Steven Townsend; Christopher G Adda; Christine Collins; Suresh Mathivanan; Gavin E Reid
Journal:  Methods       Date:  2015-04-20       Impact factor: 3.608

5.  Multiple mechanisms of N-phosphonacetyl-L-aspartate resistance in human cell lines: carbamyl-P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged.

Authors:  K A Smith; O B Chernova; R P Groves; M B Stark; J L Martínez; J N Davidson; J M Trent; T E Patterson; A Agarwal; P Duncan; M L Agarwal; G R Stark
Journal:  Proc Natl Acad Sci U S A       Date:  1997-03-04       Impact factor: 11.205

6.  Two distinct populations of exosomes are released from LIM1863 colon carcinoma cell-derived organoids.

Authors:  Bow J Tauro; David W Greening; Rommel A Mathias; Suresh Mathivanan; Hong Ji; Richard J Simpson
Journal:  Mol Cell Proteomics       Date:  2012-12-10       Impact factor: 5.911

7.  Amiloride modulates urokinase gene expression at both transcription and post-transcription levels in human colon cancer cells.

Authors:  Y Wang; J Dang; X Liang; W F Doe
Journal:  Clin Exp Metastasis       Date:  1995-05       Impact factor: 5.150

8.  Proteomics analysis of A33 immunoaffinity-purified exosomes released from the human colon tumor cell line LIM1215 reveals a tissue-specific protein signature.

Authors:  Suresh Mathivanan; Justin W E Lim; Bow J Tauro; Hong Ji; Robert L Moritz; Richard J Simpson
Journal:  Mol Cell Proteomics       Date:  2009-10-16       Impact factor: 5.911

9.  Heterogeneity in antigenic expression and radiosensitivity in human colon carcinoma cell lines.

Authors:  G Frykholm; B Glimelius; S Richter; J Carlsson
Journal:  In Vitro Cell Dev Biol       Date:  1991-12

10.  CpG island methylation is a common finding in colorectal cancer cell lines.

Authors:  C M Suter; M Norrie; S L Ku; K F Cheong; I Tomlinson; R L Ward
Journal:  Br J Cancer       Date:  2003-02-10       Impact factor: 7.640
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