| Literature DB >> 3856955 |
N C Popescu, S C Amsbaugh, J A DiPaolo, S R Tronick, S A Aaronson, D C Swan.
Abstract
Three human ras family protooncogenes, c-Ki-ras-1, and c-Ki-ras-2, and N-ras, have been mapped to chromosome bands 6p11-12, 12p11.1-12.1, and 1p11-13, respectively by in situ molecular hybridization. Certain human cancers display consistent and specific alterations involving chromosomes 1, 6, and 12. The precise chromosomal localization of ras genes will permit evaluation of the possible effect of these chromosome changes on the structure and activities of ras protooncogenes in human neoplasia.Entities:
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Year: 1985 PMID： 3856955 DOI： 10.1007/bf01534703
Source DB: PubMed Journal: Somat Cell Mol Genet ISSN： 0740-7750