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Literature DB >> 3856735

Increased secretion of type beta transforming growth factor accompanies viral transformation of cells.

M A Anzano, A B Roberts, J E De Larco, L M Wakefield, R K Assoian, N S Roche, J M Smith, J E Lazarus, M B Sporn.

Abstract

Cells transformed by Harvey or Moloney sarcoma virus secrete at least 40 times as much type beta transforming growth factor as their respective untransformed control cells. The transformed cells bind only 20 to 50% as much type beta transforming growth factor as the control cells, suggesting that transformation causes down-regulation of the type beta transforming growth factor receptor.

Entities: Disease

Mesh：

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Year: 1985 PMID： 3856735 PMCID： PMC366699 DOI： 10.1128/mcb.5.1.242-247.1985

Source DB: PubMed Journal: Mol Cell Biol ISSN： 0270-7306 Impact factor: 4.272

28 in total

1. Growth factors produced by sarcoma virus-transformed cells.

Authors: G J Todaro; J E De Larco
Journal: Cancer Res Date: 1978-11 Impact factor: 12.701

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Journal: Nature Date: 1977-06-09 Impact factor: 49.962

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Authors: J E de Larco; G J Todaro
Journal: Proc Natl Acad Sci U S A Date: 1978-08 Impact factor: 11.205

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Journal: Nature Date: 1970-08-15 Impact factor: 49.962

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Authors: J E de Larco; G J Todaro
Journal: J Cell Physiol Date: 1978-03 Impact factor: 6.384

6. Autocrine secretion and malignant transformation of cells.

Authors: M B Sporn; G J Todaro
Journal: N Engl J Med Date: 1980-10-09 Impact factor: 91.245

7. New class of transforming growth factors potentiated by epidermal growth factor: isolation from non-neoplastic tissues.

Authors: A B Roberts; M A Anzano; L C Lamb; J M Smith; M B Sporn
Journal: Proc Natl Acad Sci U S A Date: 1981-09 Impact factor: 11.205

8. Kirsten murine sarcoma virus transformed cell lines and a spontaneously transformed rat cell-line produce transforming factors.

Authors: B Ozanne; R J Fulton; P L Kaplan
Journal: J Cell Physiol Date: 1980-10 Impact factor: 6.384

9. Epidermal growth factor-like transforming growth factor. I. Isolation, chemical characterization, and potentiation by other transforming factors from feline sarcoma virus-transformed rat cells.

Authors: J Massagué
Journal: J Biol Chem Date: 1983-11-25 Impact factor: 5.157

10. Sarcoma growth factor from conditioned medium of virally transformed cells is composed of both type alpha and type beta transforming growth factors.

Authors: M A Anzano; A B Roberts; J M Smith; M B Sporn; J E De Larco
Journal: Proc Natl Acad Sci U S A Date: 1983-10 Impact factor: 11.205

39 in total

1. Effects of retinoic acid on NIH3T3 cell transformation by the H-ras oncogene.

Authors: L R Cox; J Motz; W Troll; S J Garte
Journal: J Cancer Res Clin Oncol Date: 1991 Impact factor: 4.553

2. Restoration of Smad4 in BxPC3 pancreatic cancer cells attenuates proliferation without altering angiogenesis.

Authors: Michiya Yasutome; Jason Gunn; Murray Korc
Journal: Clin Exp Metastasis Date: 2005 Impact factor: 5.150

3. Chemotherapeutic Targeting of the Transforming Growth Factor-β Pathway in Breast Cancers.

Authors: Yong-Hun Lee; William P Schiemann
Journal: Breast Cancer Manag Date: 2014

4. Autoinduction of transforming growth factor beta 1 is mediated by the AP-1 complex.

Authors: S J Kim; P Angel; R Lafyatis; K Hattori; K Y Kim; M B Sporn; M Karin; A B Roberts
Journal: Mol Cell Biol Date: 1990-04 Impact factor: 4.272

5. Rapid and selective alterations in the expression of cellular genes accompany conditional transcription of Ha-v-ras in NIH 3T3 cells.

Authors: R D Owen; M C Ostrowski
Journal: Mol Cell Biol Date: 1987-07 Impact factor: 4.272

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Authors: N E Hynes; D Taverna; I M Harwerth; F Ciardiello; D S Salomon; T Yamamoto; B Groner
Journal: Mol Cell Biol Date: 1990-08 Impact factor: 4.272

7. TGF-beta inhibits the in vitro induction of lymphokine-activated killing activity.

Authors: E A Grimm; W L Crump; A Durett; J P Hester; S Lagoo-Deenadalayan; L B Owen-Schaub
Journal: Cancer Immunol Immunother Date: 1988 Impact factor: 6.968

8. Transforming growth factor-beta can suppress tumorigenesis through effects on the putative cancer stem or early progenitor cell and committed progeny in a breast cancer xenograft model.

Authors: Binwu Tang; Naomi Yoo; Mary Vu; Mizuko Mamura; Jeong-Seok Nam; Akira Ooshima; Zhijun Du; Pierre-Yves Desprez; Miriam R Anver; Aleksandra M Michalowska; Joanna Shih; W Tony Parks; Lalage M Wakefield
Journal: Cancer Res Date: 2007-09-15 Impact factor: 12.701

9. Regulation of adhesion and growth of fibrosarcoma cells by NF-kappa B RelA involves transforming growth factor beta.

Authors: J R Perez; K A Higgins-Sochaski; J Y Maltese; R Narayanan
Journal: Mol Cell Biol Date: 1994-08 Impact factor: 4.272

10. Malignant transformation of murine fibroblasts by a human c-Ha-ras-1 oncogene does not require a functional epidermal growth factor receptor.

Authors: I A McKay; P Malone; C J Marshall; A Hall
Journal: Mol Cell Biol Date: 1986-10 Impact factor: 4.272