Corneal infiltrates and extended-wear contact lenses.

Corneal infiltrates are a relatively rare but potentially serious complication of extended-wear contact lenses. Clinical experience with a large population of extended-wear patients suggested that these infiltrates have a characteristic location and appearance which may aid in diagnosis and management. The records of 51 patients (54 eyes) with extended-wear contact lenses and corneal infiltrates were reviewed. Nearly all the infiltrates were in the peripheral cornea and 67% were located superiorly, beneath the upper lid. No permanent visual loss resulted and all patients resumed extended-wear of contact lenses following a period of appropriate management. The clinical features, management, and possible etiologies are discussed. The sample reported herein is the largest, to date, of any reported in the ophthalmic literature.