Literature DB >> 3855932

Type II collagen-induced arthritis in mice. III. Suppression of arthritis by using monoclonal and polyclonal anti-Ia antisera.

P H Wooley, H S Luthra, W P Lafuse, A Huse, J M Stuart, C S David.   

Abstract

Pretreatment of mice genetically susceptible to type II collagen-induced arthritis (CIA) with monoclonal or polyclonal antisera specific for I region gene products (Ia antigens) suppressed or delayed the onset of CIA, whereas pretreatment with anti-Ia to an irrelevant haplotype was without effect. The humoral response to type II collagen was transiently depressed 14 days after immunization but antibody levels did not differ significantly after 28 days. The peak delayed-type hypersensitivity to type II collagen was unaffected by anti-Ia treatment. Monoclonal antibody of one anti-Ia specificity enhanced both the antibody response and the arthritis incidence in one mouse strain.

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Year:  1985        PMID： 3855932

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  19 in total

Review 1.  New therapies in development for autoimmune diseases: their rationale for combination treatment.

Authors:  V Strand
Journal:  Springer Semin Immunopathol       Date:  2001

Review 2.  Immunotherapy of rheumatoid arthritis.

Authors:  R A Watts; J D Isaacs
Journal:  Ann Rheum Dis       Date:  1992-05       Impact factor: 19.103

Review 3.  Regulation of immunity by anti-T-cell antibodies.

Authors:  D Wofsy
Journal:  West J Med       Date:  1990-09

Review 4.  Combination therapy in mice: what can we learn that may be useful for understanding rheumatoid arthritis?

Authors:  R O Williams
Journal:  Springer Semin Immunopathol       Date:  1998

5.  Monoclonal antibodies and arthritis.

Authors:  M E Billingham; C Hicks; S Carney
Journal:  Agents Actions       Date:  1990-01

6.  Modulation of low-dose streptozotocin-induced diabetes in mice by administration of antibodies to I-A, I-E and I-J determinants.

Authors:  U Kiesel; M Oschilewski; M Taniguchi; H Kolb
Journal:  Diabetologia       Date:  1989-03       Impact factor: 10.122

Review 7.  What can we learn about rheumatoid arthritis from animal models?

Authors:  L Klareskog
Journal:  Springer Semin Immunopathol       Date:  1989

8.  The role of MHC class II antigens in the flare up reaction of antigen-induced arthritis in mice.

Authors:  M F van den Broek; W B van den Berg; L B van de Putte
Journal:  Agents Actions       Date:  1986-12

9.  Prevention of diabetes in nonobese diabetic mice by anti-I-A monoclonal antibodies: transfer of protection by splenic T cells.

Authors:  C Boitard; A Bendelac; M F Richard; C Carnaud; J F Bach
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

10.  Resistance to development of collagen-induced arthritis in C57BL/6 mice is due to a defect in secondary, but not in primary, immune response.

Authors:  Meng Pan; Insoo Kang; Joe Craft; Zhinan Yin
Journal:  J Clin Immunol       Date:  2004-09       Impact factor: 8.317
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