Literature DB >> 385325

Controlled blocking of hepatic artery flow with enzymatically degradable microspheres combined with oncolytic drugs.

K F Aronsen, C Hellekant, J Holmberg, U Rothman, H Teder.   

Abstract

A new method for intermittent hepatic arterial flow arrest has been used in combination with intraarterial 5-fluorouracil (5-Fu) for the treatment of secondary liver neoplasms in 12 patients. Polysaccharide microspheres with a half-life of 1 h were infused together with 5-Fu via a percutaneously introduced catheter into the hepatic artery. There were no significant side effects to the treatment. Clinical effects and overall survival were comparable to those of hepatic artery ligation.

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Year:  1979        PMID： 385325     DOI： 10.1159/000128056

Source DB:  PubMed          Journal:  Eur Surg Res        ISSN： 0014-312X            Impact factor:   1.745


  10 in total

1.  Effect of microspheres in intra-arterial chemotherapy. A study of arterio-venous shunting and passage of a labelled marker.

Authors:  H Starkhammar; L Håkansson; O Morales; J Svedberg
Journal:  Med Oncol Tumor Pharmacother       Date:  1987

Review 2.  Therapy of bladder cancer.

Authors:  K H Bichler; S Halim
Journal:  Int Urol Nephrol       Date:  1987       Impact factor: 2.370

3.  Transarterial chemoembolization with degradable starch microspheres, irinotecan, and mitomycin-C in patients with liver metastases.

Authors:  Zenichi Morise; Atsushi Sugioka; Ryoichi Kato; Junko Fujita; Sojun Hoshimoto; Takazumi Kato
Journal:  J Gastrointest Surg       Date:  2006-02       Impact factor: 3.452

Review 4.  Hepatic artery infusion and chemoembolization in the management of liver metastases.

Authors:  S Wallace; C H Carrasco; C Charnsangavej; W R Richli; K Wright; C Gianturco
Journal:  Cardiovasc Intervent Radiol       Date:  1990 Jun-Jul       Impact factor: 2.740

5.  A gamma camera method to monitor the use of degradable starch microspheres in hepatic arterial chemotherapy.

Authors:  A Britten; A Flowerdew; T Hunt; I Taylor; D Ackery; J Fleming
Journal:  Eur J Nucl Med       Date:  1989

Review 6.  [Transarterial chemoembolization of liver metastases of colorectal carcinoma using degradable starch microspheres (Spherex): personal investigations and review of the literature].

Authors:  K Wasser; F Giebel; R Fischbach; H Tesch; P Landwehr
Journal:  Radiologe       Date:  2005-07       Impact factor: 0.635

7.  Effects of multimodal treatment and hyperthermia on hepatic tumors.

Authors:  Y Tanaka; K Yamamoto; T Murata; K Nagata
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

8.  Temporary blood flow stasis with degradable starch microspheres (DSM) for liver metastases in a rat model.

Authors:  A D Flowerdew; H K Richards; I Taylor
Journal:  Gut       Date:  1987-10       Impact factor: 23.059

Review 9.  Chemo-occlusion for the treatment of liver cancer. A new technique using degradable starch microspheres.

Authors:  T Taguchi
Journal:  Clin Pharmacokinet       Date:  1994-04       Impact factor: 6.447

10.  Continuous 5-day regional chemotherapy by 5-fluorouracil in colon carcinoma: pharmacokinetic evaluation.

Authors:  J L Boublil; G Milano; R Khater; J Bourry; A Thyss; J N Bruneton; N Renée; C Philip; M Namer
Journal:  Br J Cancer       Date:  1985-07       Impact factor: 7.640
  10 in total

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