| Literature DB >> 3853 |
N Mihalakis, O J Miller, B F Erlanger.
Abstract
Highly specific antibodies were raised to histone 1 (H 1) and the histone complexes H32-H42 AND H2A-H2B, isolated by salt extraction. Antibody to H1 could detect irreversible conformational changes in acid- or urea-treated H1. The antibodies showed different reactivities with chromosomes as compared to antibodies in acid-extracted histones and should be useful in studies of native chromatin and chromosome structure.Entities:
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Year: 1976 PMID： 3853 DOI： 10.1126/science.3853
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728