Literature DB >> 3852742

Elastase digested urokinase (ED-UK).

H Sumi, T Kosugi, N Toki, H Mihara.   

Abstract

Elastase digested urokinase (ED-UK) was prepared from human high mol. wt urokinase (HMW-UK). It resembled low mol. wt urokinase (LMW-UK) in its mol. wt, specific activity, and active sites. The steady-state kinetic parameters of each enzyme for the activation of human Glu-plasminogen also resembled each other, as did their amidase parameters (with pyro-Glu-Gly-Arg-pNA).

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Year:  1985        PMID： 3852742     DOI： 10.1007/bf01964799

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  21 in total

1.  Purification and characterization of two forms of urokinase.

Authors:  M E Soberano; E B Ong; A J Johnson; M Levy; G Schoellmann
Journal:  Biochim Biophys Acta       Date:  1976-10-11

2.  Urokinase-streptokinase embolism trial. Phase 2 results. A cooperative study.

Authors: 
Journal:  JAMA       Date:  1974-09-16       Impact factor: 56.272

3.  Studies on the biochemistry of urokinase.

Authors:  E B Ong; M E Soberano; A J Johnson; G Schoellmann
Journal:  Thromb Haemost       Date:  1977-12-15       Impact factor: 5.249

4.  Human low-molecular-weight urinary urokinase. Partial characterization and preliminary sequence data of the two polypeptide chains.

Authors:  J Schaller; H Nick; E E Rickli; D Gillessen; W Lergier; R O Studer
Journal:  Eur J Biochem       Date:  1982-07

5.  The primary structure of high molecular mass urokinase from human urine. The complete amino acid sequence of the A chain.

Authors:  W A Günzler; G J Steffens; F Otting; S M Kim; E Frankus; L Flohé
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1982-10

6.  Immunochemical studies of high and low molecular forms of urokinase.

Authors:  H Sumi; N Toki; S Maehara; T Kosugi; K Akazawa; O Matsuo; H Mihara
Journal:  Acta Haematol       Date:  1982       Impact factor: 2.195

7.  A simple and rapid purification method of urokinase using a [Nalpha-(epsilon-aminocaproyl)-DL-homoarginine hexylester]-sepharose column.

Authors:  H Sumi; K Sasaki; M Muramatu
Journal:  Nihon Ketsueki Gakkai Zasshi       Date:  1978-08

8.  Low molecular weight trypsin-plasmin inhibitors isolated from papain treated urinary trypsin inhibitor.

Authors:  H Sumi; N Toki; S Takasugi; S Maehara; M Maruyama; K Akazawa; O Matsuo; H Mihara
Journal:  Thromb Haemost       Date:  1982-02-26       Impact factor: 5.249

9.  A functionally active heavy chain derived from human high molecular weight urokinase.

Authors:  H Sumi; K C Robbins
Journal:  J Biol Chem       Date:  1983-07-10       Impact factor: 5.157

10.  A comparative study of high molecular weight urokinase and low molecular weight urokinase.

Authors:  M Nobuhara; M Sakamaki; H Ohnishi; Y Suzuki
Journal:  J Biochem       Date:  1981-07       Impact factor: 3.387
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