Literature DB >> 384949

The role of prostaglandins in platelet-vessel wall interaction.

R H Bourgain, R Andries, E Finne.   

Abstract

Flurbiprofen, a cyclooxygenase inhibitor, and tranylcypromine, a PGI2 synthetase inhibitor, in topical superfusion over an arterial segment respectively decrease and increase ADP-induced local white platelet thrombus formation. Superfusion of the arterial segment with PGI2 demonstrates a dose-response related inhibition of ADP-induced thrombosis.

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Year:  1979        PMID: 384949

Source DB:  PubMed          Journal:  Arch Int Pharmacodyn Ther        ISSN: 0003-9780


  1 in total

1.  Coronary vasoconstrictor and vasodilator actions of arachidonic acid in the isolated perfused heart of the rat.

Authors:  S E Belo; J Talesnik
Journal:  Br J Pharmacol       Date:  1982-02       Impact factor: 8.739

  1 in total

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