Immunological parameters in patients with gastric cancer at different clinical stages.

Lymphocyte subpopulations, cutaneous reactivity to tuberculin and distreptase, and immunoglobulin level were investigated in 32 untreated patients with gastric cancer at different stages of advancement and in healthy controls. Statistically significant decrease in the number of T-lymphocytes, accompanied by a deficient cutaneous reactivity, as well as a decrease in the number of B-lymphocytes and lowered A, G, and M immunoglobulin concentration were found in patients with grade III cancer.