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Literature DB >> 3841805

Characterization of a cDNA clone encoding murine mitogen-regulated protein: regulation of mRNA levels in mortal and immortal cell lines.

C L Parfett, R T Hamilton, B W Howell, D R Edwards, M Nilsen-Hamilton, D T Denhardt.

Abstract

Mitogen-regulated protein (MRP) is secreted by certain immortal murine cell lines (Swiss 3T3, BNL) stimulated with serum or particular growth factors. We have identified a cDNA clone that encodes part of the protein and have confirmed that MRP is closely related to, if not identical to, the prolactin-related protein designated proliferin. MRP is not produced by primary mouse embryo fibroblasts to nearly the same extent as it is produced by many immortal or transformed lines. Control of expression of this protein by growth factors is achieved both by regulating the extent of transcription and by regulating the processing of the protein.

Entities: Gene Species

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Year: 1985 PMID： 3841805 PMCID： PMC369146 DOI： 10.1128/mcb.5.11.3289-3292.1985

Source DB: PubMed Journal: Mol Cell Biol ISSN： 0270-7306 Impact factor: 4.272

15 in total

1. Development of 3T3-like lines from Balb-c mouse embryo cultures: transformation susceptibility to SV40.

Authors: S A Aaronson; G J Todaro
Journal: J Cell Physiol Date: 1968-10 Impact factor: 6.384

2. Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors: U K Laemmli
Journal: Nature Date: 1970-08-15 Impact factor: 49.962

3. Efficient isolation of genes by using antibody probes.

Authors: R A Young; R W Davis
Journal: Proc Natl Acad Sci U S A Date: 1983-03 Impact factor: 11.205

Review 4. Intracellular degradation of newly synthesized secretory proteins.

Authors: R S Bienkowski
Journal: Biochem J Date: 1983-07-15 Impact factor: 3.857

5. Selective stimulation by mitogens of incorporation of 35S-methionine into a family of proteins released into the medium by 3T3 cells.

Authors: M Nilsen-Hamilton; J M Shapiro; S L Massoglia; R T Hamilton
Journal: Cell Date: 1980-05 Impact factor: 41.582

Review 6. Secreted proteins, intercellular communication, and the mitogenic response.

Authors: M Nilsen-Hamilton; R T Hamilton
Journal: Cell Biol Int Rep Date: 1982-09

7. Stimulation of the release of two glycoproteins from mouse 3T3 cells by growth factors and by agents that increase intralysosomal pH.

Authors: M Nilsen-Hamilton; R T Hamilton; W R Allen; S L Massoglia
Journal: Biochem Biophys Res Commun Date: 1981-07-30 Impact factor: 3.575

8. Transformed cell lines susceptible or resistant to in vivo surveillance against tumorigenesis.

Authors: P Q Patek; J L Collins; M Cohn
Journal: Nature Date: 1978-11-30 Impact factor: 49.962

9. Growth-related changes in specific mRNAs of cultured mouse cells.

Authors: D I Linzer; D Nathans
Journal: Proc Natl Acad Sci U S A Date: 1983-07 Impact factor: 11.205

10. Mouse beta 2-microglobulin cDNA clones: a screening procedure for cDNA clones corresponding to rare mRNAs.

Authors: J R Parnes; B Velan; A Felsenfeld; L Ramanathan; U Ferrini; E Appella; J G Seidman
Journal: Proc Natl Acad Sci U S A Date: 1981-04 Impact factor: 11.205

10 in total

1. A growth-responsive gene (16C8) in normal mouse fibroblasts homologous to a human collagenase inhibitor with erythroid-potentiating activity: evidence for inducible and constitutive transcripts.

Authors: D R Edwards; P Waterhouse; M L Holman; D T Denhardt
Journal: Nucleic Acids Res Date: 1986-11-25 Impact factor: 16.971

2. Participation of multiple factors, including proliferin, in the inhibition of myogenic differentiation.

Authors: E L Wilder; D I Linzer
Journal: Mol Cell Biol Date: 1989-02 Impact factor: 4.272

3. A growth-related mRNA in cultured mouse cells encodes a placental calcium binding protein.

Authors: L L Jackson-Grusby; J Swiergiel; D I Linzer
Journal: Nucleic Acids Res Date: 1987-08-25 Impact factor: 16.971

4. The mitogen-regulated protein/proliferin transcript is degraded in primary mouse embryo fibroblast but not 3T3 nuclei: altered RNA processing correlates with immortalization.

Authors: U M Malyankar; S R Rittling; A Connor; D T Denhardt
Journal: Proc Natl Acad Sci U S A Date: 1994-01-04 Impact factor: 11.205

5. Transcriptional regulation of two serum-induced RNAs in mouse fibroblasts: equivalence of one species to B2 repetitive elements.

Authors: D R Edwards; C L Parfett; D T Denhardt
Journal: Mol Cell Biol Date: 1985-11 Impact factor: 4.272

6. Molecular cloning of gene sequences regulated by tumor promoters and mitogens through protein kinase C.

Authors: M D Johnson; G M Housey; P T Kirschmeier; I B Weinstein
Journal: Mol Cell Biol Date: 1987-08 Impact factor: 4.272

7. Alpha3beta1 integrin in epidermis promotes wound angiogenesis and keratinocyte-to-endothelial-cell crosstalk through the induction of MRP3.

Authors: Kara Mitchell; Charles Szekeres; Vincenzo Milano; Kimberly B Svenson; Marit Nilsen-Hamilton; Jordan A Kreidberg; C Michael DiPersio
Journal: J Cell Sci Date: 2009-05-12 Impact factor: 5.285