Literature DB >> 3840531

Tubulin and benzimidazole-resistance in Trichostrongylus colubriformis (Nematoda).

N C Sangster, R K Prichard, E Lacey.   

Abstract

Benzimidazole treatment produced greater effects on microtubule-dependent acetylcholinesterase secretion, the presence of microtubules in intestinal cells, and colchicine binding in susceptible compared with benzimidazole-resistant Trichostrongylus colubriformis. In addition, the binding of benzimidazoles was markedly reduced in preparations from the latter strain, indicating that the mechanism of resistance to benzimidazoles in this nematode involves a reduced affinity of tubulin for benzimidazoles.

Entities:  

Mesh：

Substances：

Year:  1985        PMID： 3840531

Source DB:  PubMed          Journal:  J Parasitol        ISSN： 0022-3395            Impact factor:   1.276


  8 in total

Review 1.  Control of nematode parasites with agents acting on neuro-musculature systems: lessons for neuropeptide ligand discovery.

Authors:  Richard J Martin; Alan P Robertson
Journal:  Adv Exp Med Biol       Date:  2010       Impact factor: 2.622

2.  Dinitroaniline activity in Toxoplasma gondii expressing wild-type or mutant alpha-tubulin.

Authors:  Christopher Ma; Johnson Tran; Frank Gu; Roxanna Ochoa; Catherine Li; David Sept; Karl Werbovetz; Naomi Morrissette
Journal:  Antimicrob Agents Chemother       Date:  2010-02-09       Impact factor: 5.191

3.  Occurrence of Strongylid Nematode Parasites on Horse Farms in Berlin and Brandenburg, Germany, With High Seroprevalence of Strongylus vulgaris Infection.

Authors:  Laura Jürgenschellert; Jürgen Krücken; Eric Bousquet; Jürgen Bartz; Nina Heyer; Martin K Nielsen; Georg von Samson-Himmelstjerna
Journal:  Front Vet Sci       Date:  2022-06-10

4.  Comparative in vitro effect of artemether and albendazole on adult Toxocara canis.

Authors:  H A Shalaby; S Abdel-Shafy; K A Abdel-Rahman; A A Derbala
Journal:  Parasitol Res       Date:  2009-05-26       Impact factor: 2.289

5.  Genetic variability of the beta-tubulin genes in benzimidazole-susceptible and -resistant strains of Haemonchus contortus.

Authors:  R N Beech; R K Prichard; M E Scott
Journal:  Genetics       Date:  1994-09       Impact factor: 4.562

6.  Flowcytometric assessment of the effect of drugs on Giardia lamblia trophozoites in vitro.

Authors:  Harpreet Sandhu; Ramesh Chander Mahajan; Nirmal Kumar Ganguly
Journal:  Mol Cell Biochem       Date:  2004-10       Impact factor: 3.396

7.  Genetic and molecular analysis of a Caenorhabditis elegans beta-tubulin that conveys benzimidazole sensitivity.

Authors:  M Driscoll; E Dean; E Reilly; E Bergholz; M Chalfie
Journal:  J Cell Biol       Date:  1989-12       Impact factor: 10.539

8.  Benzimidazole resistance survey for Haemonchus, Teladorsagia and Trichostrongylus in three European countries using pyrosequencing including the development of new assays for Trichostrongylus.

Authors:  Sabrina Ramünke; Lynsey Melville; Laura Rinaldi; Hubertus Hertzberg; Theo de Waal; Georg von Samson-Himmelstjerna; Giuseppe Cringoli; Fabien Mavrot; Philip Skuce; Jürgen Krücken; Janina Demeler
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2016-10-08       Impact factor: 4.077
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.