Literature DB >> 3840114

Oestrogenic potency of genistin and daidzin in mice.

E Farmakalidis, J N Hathcock, P A Murphy.   

Abstract

The oestrogenic activity of genistin and daidzin was investigated in the B6D2F1 strain of mouse. Diethylstilboestrol and genistein were used as positive controls. The oestrogenic response to 1.5 mg genistin was equivalent to that of 1 mg genistein, giving a 1:1 molar relationship in oestrogenic activity between genistin and genistein. The oestrogenic response to 3.8 mg daidzin was equivalent to that of 1 mg genistein. Analysis of the blood obtained from the mice in this experiment failed to reveal any free genistein or daidzein in the plasma.

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Year:  1985        PMID： 3840114     DOI： 10.1016/0278-6915(85)90268-6

Source DB:  PubMed          Journal:  Food Chem Toxicol        ISSN： 0278-6915            Impact factor:   6.023


  7 in total

Review 1.  NTP-CERHR expert panel report on the reproductive and developmental toxicity of genistein.

Authors:  Karl K Rozman; Jatinder Bhatia; Antonia M Calafat; Christina Chambers; Martine Culty; Ruth A Etzel; Jodi A Flaws; Deborah K Hansen; Patricia B Hoyer; Elizabeth H Jeffery; James S Kesner; Sue Marty; John A Thomas; David Umbach
Journal:  Birth Defects Res B Dev Reprod Toxicol       Date:  2006-12

2.  Dietary and environmental estrogens and antiestrogens and their possible role in human disease.

Authors:  S H Safe
Journal:  Environ Sci Pollut Res Int       Date:  1994-01       Impact factor: 4.223

3.  Inhibitory effects of genistein and resveratrol on guinea pig gallbladder contractility in vitro.

Authors:  Long-De Wang; Xiao-Qing Qiu; Zhi-Feng Tian; Ying-Fu Zhang; Hong-Fang Li
Journal:  World J Gastroenterol       Date:  2008-08-21       Impact factor: 5.742

4.  Cumulative dietary energy intake determines the onset of puberty in female rats.

Authors:  Jenny Odum; Helen Tinwell; Graham Tobin; John Ashby
Journal:  Environ Health Perspect       Date:  2004-11       Impact factor: 9.031

5.  Identification of estrogen-regulated genes by microarray analysis of the uterus of immature rats exposed to endocrine disrupting chemicals.

Authors:  Eui-Ju Hong; Se-Hyung Park; Kyung-Chul Choi; Peter C K Leung; Eui-Bae Jeung
Journal:  Reprod Biol Endocrinol       Date:  2006-09-29       Impact factor: 5.211

6.  Comparison among Activities and Isoflavonoids from Pueraria thunbergiana Aerial Parts and Root.

Authors:  Eunjung Son; Jong-Moon Yoon; Bong-Jeun An; Yun Mi Lee; Jimin Cha; Gyeong-Yup Chi; Dong-Seon Kim
Journal:  Molecules       Date:  2019-03-05       Impact factor: 4.411

7.  The OECD program to validate the rat uterotrophic bioassay. Phase 2: dietary phytoestrogen analyses.

Authors:  William Owens; John Ashby; Jenny Odum; Lesley Onyon
Journal:  Environ Health Perspect       Date:  2003-09       Impact factor: 9.031
  7 in total

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