Literature DB >> 3840047

Peptide YY (PYY), a potent orexigenic agent.

J E Morley, A S Levine, M Grace, J Kneip.   

Abstract

Peptide YY (PYY) enhances feeding and drinking more potently than does neuropeptide Y after central administration. Chronic administration of PYY every 6 h for 48 h causes massive food ingestion. Tolerance to this effect of PYY does not appear to develop. This data suggests that PYY is one of the most potent orexigenic substances yet to be identified. PYY may play a role in the pathogenesis of bulimic syndromes.

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Year:  1985        PMID： 3840047     DOI： 10.1016/0006-8993(85)91490-8

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  18 in total

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