Literature DB >> 3839531

Dependence of solute solubility parameters on solvent polarity.

A Martin, P L Wu, Z Liron, S Cohen.   

Abstract

In nonpolar solvents a solute may self-associate through polar interactions, exposing its nonpolar surface to a solvent with a low solubility parameter, delta 1. In polar solvents a solute is solvated, presumably, by the polar groups of the solvent. This "chameleonic" effect results in different solubility parameters for a solute, depending on the polarity of the solvent. This report presents data for solute solubility parameters in solvents of variable polarity and gives suggestions for dealing with the chameleonic effect associated with solute-solvent interaction.

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Year:  1985        PMID: 3839531     DOI: 10.1002/jps.2600740611

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  2 in total

1.  Solubility prediction of satranidazole in propylene glycol-water mixtures using extended hildebrand solubility approach.

Authors:  P B Rathi
Journal:  Indian J Pharm Sci       Date:  2011-11       Impact factor: 0.975

2.  Effects of Solvents, Emulsions, Cosolvents, and Complexions on Ex Vivo Mouse Myometrial Contractility.

Authors:  Christopher J Hansen; Shajila Siricilla; Naoko Boatwright; Jackson H Rogers; Melissa E Kumi; Jennifer Herington
Journal:  Reprod Sci       Date:  2021-04-14       Impact factor: 3.060

  2 in total

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