Literature DB >> 38395

Myo-inositol-1-phosphate synthase from streptomyces griseus (studies on the biosynthesis of cyclitols, XXXVIII).

F Pittner, I I Tovarova, E Y Kornitskaya, A S Khokhlov, O Hoffmann-Ostenhof.   

Abstract

It could be shown that Streptomyces griseus, the microorganism producing the antibiotic streptomycin and also mutant strains of this species that cannot synthesize streptomycin, possess myo-inositol-1-phosphate synthase (EC 5.5.1.4), the enzyme cyclizing D-glucose 6-phosphate. The enzyme isolated from that organism is extremely instable, its molecular weight is approximately 260,000, and it requires a divalent metal ion for its activity. This is the first instance that an enzyme of this specificity has been found in a prokaryotic organism.

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Year:  1979        PMID： 38395     DOI： 10.1007/bf00211140

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  8 in total

1.  Studies on the biosynthesis of cyclitols, XXXVII. On mechanism and function of Schiff's base formation as an intermediary reaction step of myo-inositol-1-phosphate synthase from rat testicles.

Authors:  F Pittner; O Hoffmann-Ostenhof
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1978-10

2.  Biosynthesis of myo-inositol in rat mammary gland. Isolation and properties of the enzymes.

Authors:  W F Naccarato; R E Ray; W W Wells
Journal:  Arch Biochem Biophys       Date:  1974-09       Impact factor: 4.013

3.  Studies on the biosynthesis of cyclitols, XXXV. On the mechanism of action of myo-inositol-1-phosphate synthase from rat testicles.

Authors:  F Pittner; O Hoffmann-Ostenhof
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1976-12

4.  [Biosynthesis of myoinositol and its incorporation into the phospholipids of Escherichia coli].

Authors:  V Weisshäupl; O Scheiner; P Dworsky; O Hoffmann-Ostenhof
Journal:  Z Allg Mikrobiol       Date:  1976

5.  Studies on the streptomycin biosynthesis.

Authors:  A S Khokhlov; I I Tovarova
Journal:  Postepy Hig Med Dosw       Date:  1972 Jul-Aug       Impact factor: 0.270

6.  Enzymatic synthesis of streptidine from scyllo-inosamine.

Authors:  J B Walker; M S Walker
Journal:  Biochemistry       Date:  1967-12       Impact factor: 3.162

7.  A colorimetric determination of inositol monophosphates as an assay for D-glucose 6-phosphate-1L-myoinositol 1-phosphate cyclase.

Authors:  J E Barnett; R E Brice; D L Corina
Journal:  Biochem J       Date:  1970-09       Impact factor: 3.857

8.  The mechanism of glucose 6-phosphate-D-myo-inositol 1-phosphate cyclase of rat testis. The involvement of hydrogen atoms.

Authors:  J E Barnett; D L Corina
Journal:  Biochem J       Date:  1968-06       Impact factor: 3.857
  8 in total
  2 in total

1.  Preparation of homogeneous crystals of myo-inositol 1-phosphate synthase from rat testicles--further data on the chemical and catalytic properties of the enzyme (studies on the biosynthesis cyclitols, XXXIX).

Authors:  F Pittner; O Hoffmann-Ostenhof
Journal:  Mol Cell Biochem       Date:  1979-12-14       Impact factor: 3.396

2.  Fungal and Prokaryotic Activities in the Marine Subsurface Biosphere at Peru Margin and Canterbury Basin Inferred from RNA-Based Analyses and Microscopy.

Authors:  Maria G Pachiadaki; Vanessa Rédou; David J Beaudoin; Gaëtan Burgaud; Virginia P Edgcomb
Journal:  Front Microbiol       Date:  2016-06-09       Impact factor: 5.640
  2 in total

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