Literature DB >> 3838940

Antihepatoxic constituents of Garcinia kola seeds.

M M Iwu.   

Abstract

Kolaviron, a fraction of defatted methanolic extract and biflavanones of Garcinia kola seeds significantly antagonized the lethal poisoning of mice with phalloidin. Garcinia biflavanones GB1, GB2 and kolaflavanone were isolated as the active constituents.

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Year:  1985        PMID： 3838940     DOI： 10.1007/bf02007729

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  3 in total

1.  Prevention of silybin of phalloidin-induced acute hepatoxicity.

Authors:  B Tuchweber; R Sieck; W Trost
Journal:  Toxicol Appl Pharmacol       Date:  1979-11       Impact factor: 4.219

2.  Kolanone, a novel polyisoprenylated benzophenone with antimicrobial properties from the fruit of Garcinia kola.

Authors:  R A Hussain; A G Owegby; P Parimoo; P G Waterman
Journal:  Planta Med       Date:  1982-02       Impact factor: 3.352

3.  Stem bark alkaloids of Rauwolfia vomitoria.

Authors:  M M Iwu; W E Court
Journal:  Planta Med       Date:  1982-06       Impact factor: 3.352
  3 in total
  18 in total

1.  Ameliorative effect of kolaviron, a biflavonoid complex from Garcinia kola seeds against scopolamine-induced memory impairment in rats: role of antioxidant defense system.

Authors:  Ismail O Ishola; Folasade M Adamson; Olufunmilayo O Adeyemi
Journal:  Metab Brain Dis       Date:  2016-09-08       Impact factor: 3.584

2.  Kolaviron, a Garcinia kola biflavonoid complex, protects against ischemia/reperfusion injury: pertinent mechanistic insights from biochemical and physical evaluations in rat brain.

Authors:  Afolabi C Akinmoladun; Bolanle L Akinrinola; M Tolulope Olaleye; Ebenezer O Farombi
Journal:  Neurochem Res       Date:  2015-02-01       Impact factor: 3.996

3.  Cerebellar Molecular and Cellular Characterization in Rat Models of Alzheimer's Disease: Neuroprotective Mechanisms of Garcinia Biflavonoid Complex.

Authors:  Olayemi Joseph Olajide; Anita Temi Ugbosanmi; Bernard Ufuoma Enaibe; Kehinde Yomi Ogunrinola; Susan Folashade Lewu; Nnaemeka Tobechukwu Asogwa; Tosan Akapa; Aminu Imam; Abdulmumin Ibrahim; Ismail Temitayo Gbadamosi; Emmanuel Olusola Yawson
Journal:  Ann Neurosci       Date:  2017-04-21

4.  Anti-inflammatory effects of kolaviron modulate the expressions of inflammatory marker genes, inhibit transcription factors ERK1/2, p-JNK, NF-κB, and activate Akt expressions in the 93RS2 Sertoli cell lines.

Authors:  Sunny O Abarikwu
Journal:  Mol Cell Biochem       Date:  2014-12-27       Impact factor: 3.396

5.  Preliminary in vitro antisickilng properties of crude juice extracts of Persia Americana, Citrus sinensis, Carica papaya and Ciklavit®.

Authors:  E E J Iweala; F O Uhegbu; G N Ogu
Journal:  Afr J Tradit Complement Altern Med       Date:  2009-12-30

6.  Kolaviron was protective against sodium azide (NaN3) induced oxidative stress in the prefrontal cortex.

Authors:  Olayemi J Olajide; Bernard U Enaibe; Oluwamolakun O Bankole; Oluwole B Akinola; Babafemi J Laoye; Olalekan M Ogundele
Journal:  Metab Brain Dis       Date:  2015-04-29       Impact factor: 3.584

7.  Renal histoarchitectural changes in nevirapine therapy: possible role of kolaviron and vitamin C in an experimental animal model.

Authors:  Ugochukwu Offor; Sunday Adelaja Ajayi; Isaac Ayoola Jegede; Salem Kharwa; Edwin Coleridge Naidu; Onyemaechi Okpara Azu
Journal:  Afr Health Sci       Date:  2017-03       Impact factor: 0.927

8.  Inhibition of neuroinflammation in BV2 microglia by the biflavonoid kolaviron is dependent on the Nrf2/ARE antioxidant protective mechanism.

Authors:  Samuel A Onasanwo; Ravikanth Velagapudi; Abdelmeneim El-Bakoush; Olumayokun A Olajide
Journal:  Mol Cell Biochem       Date:  2016-02-02       Impact factor: 3.396

Review 9.  Antioxidative and chemopreventive properties of Vernonia amygdalina and Garcinia biflavonoid.

Authors:  Ebenezer O Farombi; Olatunde Owoeye
Journal:  Int J Environ Res Public Health       Date:  2011-06-23       Impact factor: 3.390

10.  Effect of dehusked Garcinia kola seeds on the overall pharmacokinetics of quinine in healthy Nigerian volunteers.

Authors:  Sharon I Igbinoba; Cyprian O Onyeji; Moses A Akanmu; Julius O Soyinka; Srirama Sarma V V Pullela; James M Cook; Thomas I Nathaniel
Journal:  J Clin Pharmacol       Date:  2014-12-22       Impact factor: 2.860
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