Literature DB >> 3838872

New cephalosporins cefotaxime, cefpimizole, BMY 28142, and HR 810 in experimental pneumococcal meningitis in rabbits.

M G Täuber, C J Hackbarth, K G Scott, M G Rusnak, M A Sande.   

Abstract

Four new cephalosporins, cefotaxime, cefpimizole (U 63196E), BMY 28142, and HR 810 were evaluated in experimental pneumococcal meningitis. Cefotaxime penetrated only moderately into the cerebrospinal fluid of rabbits with meningitis, whereas cefpimizole, BMY 28142, and HR 810 all exhibited unusually good penetration. The bactericidal activity in infected cerebrospinal fluid was comparable for the four drugs.

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Year:  1985        PMID： 3838872      PMCID： PMC176273          DOI： 10.1128/AAC.27.3.340

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  9 in total

1.  Antibacterial activity of beta-lactam antibiotics in experimental meningitis due to Streptococcus pneumoniae.

Authors:  M G Täuber; C A Doroshow; C J Hackbarth; M G Rusnak; T A Drake; M A Sande
Journal:  J Infect Dis       Date:  1984-04       Impact factor: 5.226

2.  Antibiotic therapy of bacterial meningitis: lessons we've learned.

Authors:  M A Sande
Journal:  Am J Med       Date:  1981-10       Impact factor: 4.965

3.  Factors influencing the penetration and activity of antibiotics in experimental meningitis.

Authors:  M A Sande
Journal:  J Infect       Date:  1981-03       Impact factor: 6.072

4.  Bactericidal versus bacteriostatic antibiotic therapy of experimental pneumococcal meningitis in rabbits.

Authors:  W M Scheld; M A Sande
Journal:  J Clin Invest       Date:  1983-03       Impact factor: 14.808

5.  Cephalosporin antibiotics in therapy of experimental Streptococcus pneumoniae and Haemophilus influenzae meningitis in rabbits.

Authors:  M A Sande; R J Sherertz; O Zak; L J Strausbaugh
Journal:  J Infect Dis       Date:  1978-05       Impact factor: 5.226

6.  Pharmacokinetics and bacteriological efficacy of cefoperazone, ceftriaxone, and moxalactam in experimental Streptococcus pneumoniae and Haemophilus influenzae meningitis.

Authors:  G H McCracken; J D Nelson; L Grimm
Journal:  Antimicrob Agents Chemother       Date:  1982-02       Impact factor: 5.191

7.  Effect of probenecid on cerebrospinal fluid concentrations of penicillin and cephalosporin derivatives.

Authors:  R G Dacey; M A Sande
Journal:  Antimicrob Agents Chemother       Date:  1974-10       Impact factor: 5.191

8.  Effects of subminimal inhibitory concentrations of antibiotics in experimental infections.

Authors:  O Zak; F Kradolfer
Journal:  Rev Infect Dis       Date:  1979 Sep-Oct

9.  Comparison of cefoperazone with penicillin, ampicillin, gentamicin, and chloramphenicol in the therapy of experimental meningitis.

Authors:  W M Scheld; J P Brodeur; M A Sande; G M Alliegro
Journal:  Antimicrob Agents Chemother       Date:  1982-10       Impact factor: 5.191
  9 in total
  28 in total

1.  Synergy between trovafloxacin and ceftriaxone against penicillin-resistant pneumococci in the rabbit meningitis model and in vitro.

Authors:  P Cottagnoud; F Acosta; M Cottagnoud; K Neftel; M G Täuber
Journal:  Antimicrob Agents Chemother       Date:  2000-08       Impact factor: 5.191

2.  Streptococcus pneumoniae: Activity of Newer Agents Against Penicillin-Resistant Strains.

Authors: 
Journal:  Curr Infect Dis Rep       Date:  1999-04       Impact factor: 3.725

3.  Effects of age and gender on pharmacokinetics of cefepime.

Authors:  R H Barbhaiya; C A Knupp; K A Pittman
Journal:  Antimicrob Agents Chemother       Date:  1992-06       Impact factor: 5.191

4.  Safety, tolerance, and pharmacokinetic evaluation of cefepime after administration of single intravenous doses.

Authors:  R H Barbhaiya; S T Forgue; C R Gleason; C A Knupp; K A Pittman; D J Weidler; R R Martin
Journal:  Antimicrob Agents Chemother       Date:  1990-06       Impact factor: 5.191

5.  Acute Bacterial Meningitis: Challenges to Better Antibiotic Therapy.

Authors:  Colin Kietzman; Elaine Tuomanen
Journal:  ACS Infect Dis       Date:  2019-07-03       Impact factor: 5.084

6.  Levofloxacin-ceftriaxone combination attenuates lung inflammation in a mouse model of bacteremic pneumonia caused by multidrug-resistant Streptococcus pneumoniae via inhibition of cytolytic activities of pneumolysin and autolysin.

Authors:  Arnab Majhi; Rana Adhikary; Aritra Bhattacharyya; Sayantika Mahanti; Biswadev Bishayi
Journal:  Antimicrob Agents Chemother       Date:  2014-06-23       Impact factor: 5.191

7.  Efficacy of BMY-28142 in experimental bacteremia and meningitis caused by Escherichia coli and group B streptococci.

Authors:  K S Kim; A S Bayer
Journal:  Antimicrob Agents Chemother       Date:  1985-07       Impact factor: 5.191

8.  Comparative in vitro activity of cefepime (BMY 28142) against multiresistant nosocomial isolates of Pseudomonas aeruginosa.

Authors:  D Voutsinas; T Mavroudis; A Avlamis; H Giamarellou
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1989-10       Impact factor: 3.267

Review 9.  Cefepime clinical pharmacokinetics.

Authors:  M P Okamoto; R K Nakahiro; A Chin; A Bedikian
Journal:  Clin Pharmacokinet       Date:  1993-08       Impact factor: 6.447

10.  Cefepime compared with ceftazidime as initial therapy for serious bacterial infections and sepsis syndrome.

Authors:  H Kieft; A I Hoepelman; M Rozenberg-Arska; J M Branger; J H Voskuil; A B Geers; M Kluyver; H C Hart; E Poest-Clement; L van Beugen
Journal:  Antimicrob Agents Chemother       Date:  1994-03       Impact factor: 5.191
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