Literature DB >> 3838805

Absorption of iohexol from cerebrospinal fluid to blood: pharmacokinetics in humans.

B Olsson, O P Eldevik, T A Grønnerød.   

Abstract

The absorption of iohexol from the subarachnoid space was studied in 9 patients. Serum concentrations of iohexol were measured for a minimum of 24 hours after injection. Peak serum concentrations were observed after 2.2 (1.7-2.7) hours. The half-life of the subsequent decrease in serum concentrations was 3.4 (2.2-7.9) hours. Concentrations of iohexol in cerebrospinal fluid were 0.29-4.3 mg I/ml 24 hours after injection (7 patients). Serum and cerebrospinal fluid concentrations of iohexol are comparable to those found after intrathecal injection of metrizamide.

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Year:  1985        PMID： 3838805     DOI： 10.1007/bf00343791

Source DB:  PubMed          Journal:  Neuroradiology        ISSN： 0028-3940            Impact factor:   2.804


  10 in total

1.  The cerebrospinal fluid valves.

Authors:  K WELCH; V FRIEDMAN
Journal:  Brain       Date:  1960-09       Impact factor: 13.501

2.  Iohexol. A non-ionic contrast medium. Pharmacology and toxicology.

Authors: 
Journal:  Acta Radiol Suppl       Date:  1980

3.  Pharmacokinetic analysis and calculations using a program for the minicalculator TI-59.

Authors:  F Nielsen-Kudsk
Journal:  Int J Biomed Comput       Date:  1981-01

4.  Elimination of aqueous myelographic contrast media from the subarachnoid space.

Authors:  O P Eldevik; V M Haughton; E A Sasse
Journal:  Invest Radiol       Date:  1980 Nov-Dec       Impact factor: 6.016

5.  A multiregional kinetics model for cerebrospinal fluid.

Authors:  C L Partain; H P Wu; E V Staab; R E Johnston
Journal:  Radiology       Date:  1978-06       Impact factor: 11.105

6.  Absorption of metrizamide from cereb rospinal fluid to blood: pharmacokinetics in humans.

Authors:  K Golman
Journal:  J Pharm Sci       Date:  1975-03       Impact factor: 3.534

7.  Iohexol in lumbar myelography: preliminary results from an open, noncomparative multicenter clinical study.

Authors:  O P Eldevik; P Nakstad; B E Kendall; T Hindmarsh
Journal:  AJNR Am J Neuroradiol       Date:  1983 May-Jun       Impact factor: 3.825

8.  Absorption of a non-ionic contrast agent from cerebrospinal fluid to blood.

Authors:  K Golman; I Wiik; S Salvesen
Journal:  Neuroradiology       Date:  1979-12-12       Impact factor: 2.804

9.  Human pharmacokinetics of iohexol. A new nonionic contrast medium.

Authors:  B Olsson; A Aulie; K Sveen; E Andrew
Journal:  Invest Radiol       Date:  1983 Mar-Apr       Impact factor: 6.016

10.  The effect of position of patient on the passage of metrizamide (Amipaque), meglumine locarmate (Dimer X) and ioserinate (Myelografin) into the blood after lumbar myelography.

Authors:  U Speck; R Schmidt; V Volkhardt; H Vogelsang
Journal:  Neuroradiology       Date:  1978-02-17       Impact factor: 2.804
  10 in total
  1 in total

Review 1.  Pathogenesis of syringomyelia associated with Chiari type 1 malformation: review of evidences and proposal of a new hypothesis.

Authors:  Izumi Koyanagi; Kiyohiro Houkin
Journal:  Neurosurg Rev       Date:  2010-06-08       Impact factor: 3.042
  1 in total

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