Literature DB >> 3838347

Low-dose 131I in treatment of Graves' disease.

C P Lowdell, H J Dobbs, G S Spathis, V R McCready, D O Cosgrove, C L Harmer.   

Abstract

One hundred and sixty-four patients with Graves' disease were treated with low-dose radioiodine (2 mCi), with a mean follow up of 4 1/2 years. At this time 74 (45%) were euthyroid having had a single dose, with a total of 131 (80%) being controlled with one or more doses. Three (2%) were still toxic but their mean follow up was only 3 years. Thirty (18%) were rendered hypothyroid, two-thirds of these after a single dose of 2 mCi 131I. The one-year incidence of hypothyroidism was 6%, with an incidence at 6 years of 20%. Previous surgery, medical treatment and thyroid antibody status appeared to have no influence on the outcome.

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Year:  1985        PMID： 3838347      PMCID： PMC1289633          DOI： 10.1177/014107688507800305

Source DB:  PubMed          Journal:  J R Soc Med        ISSN： 0141-0768            Impact factor:   5.344


  23 in total

1.  Comparison of high and low dosage levels of 131-I in the treatment of thyrotoxicosis.

Authors:  G A Hagen; R P Ouellette; E M Chapman
Journal:  N Engl J Med       Date:  1967-09-14       Impact factor: 91.245

2.  Low-dosage 131-I therapy of thyrotoxicosis (diffuse goiters). A five-year follow-up study.

Authors:  J L Cevallos; G A Hagen; F Maloof; E M Chapman
Journal:  N Engl J Med       Date:  1974-01-17       Impact factor: 91.245

3.  Hypothyroidism after low-dose 131 I treatment of hyperthyroidism.

Authors:  J A Glennon; E S Gordon; C T Sawin
Journal:  Ann Intern Med       Date:  1972-05       Impact factor: 25.391

4.  Incidence of leukemia following treatment of hyperthyroidism. Preliminary report of the Cooperative Thyrotoxicosis Therapy Follow-Up Study.

Authors:  E L Saenger; G E Thoma; E A Tompkins
Journal:  JAMA       Date:  1968-09-16       Impact factor: 56.272

5.  [Longsterm results of 131I treatment of hyperthyroidism--factors influencing the incidence of hypothyroidism (author's transl)].

Authors:  N Hamada; K Ito; T Mimura; N Momotani; Y Nishikawa; E Ino; Y Ban; T Tsuchiya
Journal:  Kaku Igaku       Date:  1979-12

Review 6.  The treatment of hyperthyroidism with iodine-131.

Authors:  W H Beierwaltes
Journal:  Semin Nucl Med       Date:  1978-01       Impact factor: 4.446

7.  Hyperthyroidism in the land of Graves: results of treatment by surgery, radio-iodine and carbimazole in 837 cases.

Authors:  D Sugrue; M McEvoy; J Feely; M I Drury
Journal:  Q J Med       Date:  1980

8.  Incidence of hypothyroidism after radioactive iodine therapy for thyrotoxicosis in Hong Kong Chinese.

Authors:  J D Best; V Chan; R Khoo; C S Teng; C Wang; R T Yeung
Journal:  Clin Radiol       Date:  1981-01       Impact factor: 2.350

9.  Hypothyroidism following 131I therapy for hyperthyroidism in relation to immunologic parameters.

Authors:  G Lundell; L E Holm
Journal:  Acta Radiol Oncol       Date:  1980

10.  Long term follow up of patients treated for hyperthyroidism with low dose radioactive iodine.

Authors:  A L Blair; D C Lowe; D R Hadden; J A Weaver; D A Montgomery
Journal:  Ulster Med J       Date:  1980
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  4 in total

1.  Low-dose radioiodine given six-monthly in Graves' disease.

Authors:  P J Hoskin; G S Spathis; V R McCready; D O Cosgrove; C L Harmer
Journal:  J R Soc Med       Date:  1985-11       Impact factor: 5.344

2.  Dose-response study on thyrotoxic patients undergoing positron emission tomography and radioiodine therapy.

Authors:  M A Flower; A al-Saadi; C L Harmer; V R McCready; R J Ott
Journal:  Eur J Nucl Med       Date:  1994-06

3.  A mathematical model of optimized radioiodine-131 therapy of Graves' hyperthyroidism.

Authors:  Suhail AR Doi; Issa Loutfi; Kamal AS Al-Shoumer
Journal:  BMC Nucl Med       Date:  2001

4.  Effectiveness of Fixed Dose Radioactive Iodine (RAI) for the Treatment of Hyperthyroidism: Experience of a Teaching Hospital in South West Nigeria.

Authors:  John Enyi Ejeh M; Karounwi Omotayo Ogunjobi; John Enyi Ejeh; Kayode Solomon Adedapo; Joshua F Eniojukan
Journal:  Mol Imaging Radionucl Ther       Date:  2013-08-01
  4 in total

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