Literature DB >> 3838246

Neuropeptide Y-like immunoreactivity in neuritic plaques of Alzheimer's disease.

D Dawbarn, P C Emson.   

Abstract

Alzheimer's disease, a form of senile dementia, is characterized by the presence of neuritic plaques and neurofibrillary tangles throughout the cortex and hippocampus. This study demonstrates the presence of neuropeptide Y-like immunoreactivity within 10-20% of neuritic plaques. Neuropeptide Y is a 36 amino acid peptide which is distributed unevenly throughout the brain and has an interneuronal location.

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Year:  1985        PMID: 3838246     DOI: 10.1016/0006-291x(85)90604-7

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  2 in total

1.  Somatostatin-like immunoreactivity and substance-P-like immunoreactivity in the CSF of patients with senile dementia of Alzheimer type, multi-infarct syndrome and communicating hydrocephalus.

Authors:  H Cramer; D Schaudt; K Rissler; D Strubel; J M Warter; F Kuntzmann
Journal:  J Neurol       Date:  1985       Impact factor: 4.849

2.  Distribution of neuropeptide Y in the prosencephalon of man and cotton-head tamarin (Saguinus oedipus): colocalization with somatostatin in neurons of striatum and amygdala.

Authors:  M Schwartzberg; J Unger; A Weindl; W Lange
Journal:  Anat Embryol (Berl)       Date:  1990
  2 in total

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