Literature DB >> 3838197

Phospholipid composition of guinea pig lung lavage.

A Q Khan, M O Sikpi, S K Das.   

Abstract

Phospholipids from guinea pig lung lavage were analyzed. The total lavage phospholipid content was 2.65 + 0.67 mg per gram of lung, which accounted for 85% of the total lipids in lung wash. Phosphatidylcholine (PC) accounted for over 60% of the total phospholipids. The other phospholipid fractions, in order of predominance, were phosphatidylinositol (PI), phosphatidylserine (PS), sphingomyelin (SPH), phosphatidylethanolamine (PE), phosphatidylglycerol (PG) and lysophosphatidyl-choline (LPC). Disaturated phosphatidylcholine (DSPC) comprised 80% of the total PC, and it contained mostly palmitic acid. The DSPC content of the lung lavage fluid per square meter of alveolar surface area was 5.76 +/- 0.42 mg.

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Year:  1985        PMID: 3838197     DOI: 10.1007/bf02534355

Source DB:  PubMed          Journal:  Lipids        ISSN: 0024-4201            Impact factor:   1.880


  35 in total

1.  Phosphorus assay in column chromatography.

Authors:  G R BARTLETT
Journal:  J Biol Chem       Date:  1959-03       Impact factor: 5.157

2.  Composition of surface-active material isolated from beef lung.

Authors:  M H KLAUS; J A CLEMENTS; R J HAVEL
Journal:  Proc Natl Acad Sci U S A       Date:  1961-11-15       Impact factor: 11.205

3.  The identification of phosphatidylglycerol in the rat, rabbit, monkey and human lung.

Authors:  S A Rooney; P M Canavan; E K Motoyama
Journal:  Biochim Biophys Acta       Date:  1974-07-26

4.  Rapid incorporation of palmitate into lung: site and metabolic fate.

Authors:  H K Darrah; J Hedley-Whyte
Journal:  J Appl Physiol       Date:  1973-02       Impact factor: 3.531

5.  Surface active materials from dog lung. I. Method of isolation.

Authors:  R J King; J A Clements
Journal:  Am J Physiol       Date:  1972-09

6.  Pulmonary surfactant and evolution of the lungs.

Authors:  J A Clements; J Nellenbogen; H J Trahan
Journal:  Science       Date:  1970-08-07       Impact factor: 47.728

7.  Isolation, characterization, and surface chemistry of a surface-active fraction from dog lung.

Authors:  M F Frosolono; B L Charms; R Pawlowski; S Slivka
Journal:  J Lipid Res       Date:  1970-09       Impact factor: 5.922

8.  Comparison of the composition and surface activity of "alveolar" and whole lung lipids in the dog.

Authors:  T E Morgan; T N Finley; H Fialkow
Journal:  Biochim Biophys Acta       Date:  1965-10-04

9.  Phosphatidylglycerol-deficient lung surfactant has normal properties.

Authors:  O S Beppu; J A Clements; J Goerke
Journal:  J Appl Physiol Respir Environ Exerc Physiol       Date:  1983-08

10.  Quantification of surfactant phospholipids in the dog lung.

Authors:  S F Ryan; S A Hashim; G Cernansky; C R Barrett; A L Bell; D F Liau
Journal:  J Lipid Res       Date:  1980-11       Impact factor: 5.922

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  3 in total

1.  Mainstream and sidestream cigarette smoke exposure increases Ca2+-dependent phospholipid binding proteins in guinea pig alveolar type II cells.

Authors:  Salil K Das; Francis H C Tsao; Shyamali Mukherjee
Journal:  Mol Cell Biochem       Date:  2002-02       Impact factor: 3.396

2.  Effects of aging on cholinephosphotransferase activity on guinea pig lung mitochondria and microsomes.

Authors:  S K Das; P Chakrabarti; S Mukherjee
Journal:  Mol Cell Biochem       Date:  1993-04-07       Impact factor: 3.396

3.  Identification of calcium-dependent phospholipid-binding proteins (annexins) from guinea pig alveolar type II cells.

Authors:  S K Das; P Chakrabarti; F H Tsao; T Nayyar; S Mukherjee
Journal:  Mol Cell Biochem       Date:  1992-09-22       Impact factor: 3.396

  3 in total

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